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文件

A2754

Sigma-Aldrich

腺苷-5'-二磷酸 钠盐

bacterial, ≥95% (HPLC)

别名:

ADP钠盐, ADP

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About This Item

经验公式（希尔记法）:
C10H15N5O10P2
CAS号:
20398-34-9
分子量:
427.20
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
24890690
NACRES:
NA.51

生物来源

bacterial

质量水平

300

检测方案

≥95% (HPLC)

形式

powder

储存温度

−20°C

SMILES字符串

[Na].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(O)=O)C(O)C3O

InChI

1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1

InChI key

XTWYTFMLZFPYCI-KQYNXXCUSA-N

基因信息

human ... HSP90AA1(3320) , P2RY1(5028)

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相关类别

一般描述

5′-二磷酸腺苷（ADP）是一种通过 FOF1-ATP 合酶转化为 ATP 而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP也可通过单磷酸腺苷酸（AMP）的腺苷酸激酶催化反应得到。ADP是一种血小板激动剂，由血小板致密颗粒分泌。它通过其与ADP受体P2Y1和P2Y12的相互作用影响血小板活化。ADP在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。

应用

5′-二磷酸腺苷钠盐已用作：
  • 血小板聚集的阳性对照，用聚焦仪分析纯化解聚素的抗血小板活性。
  • 制备原液以进行线粒体应激实验。
  • 流式细胞术分析中的阳性对照品，用于研究五聚体C反应蛋白（pCRP）和单体CRP（mCRP）对血小板CD62p（P-选择素）表达的影响。
  • 血小板激动剂，刺激血小板聚集。

储存分类代码

11 - Combustible Solids

WGK

nwg

闪点(°F)

Not applicable

闪点(°C)

Not applicable

分析证书(COA)

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What is the solubility of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?

    ADP sodium salt is soluble in water at a concentration of 50 mg/mL.

  4. What is the solution stability of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?

    ADP sodium salt is stable in solution for several months when stored at pH 7 and at -20 °C.  When a solution is stored at pH 7 and 4 °C, the solution is stable for several days. It is unstable in acid.

  5. What are the spectral properties of Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754?

    The millimolar extinction coefficient of a pH 7 solution of ADP sodium salt is 15.4 at the absorbance maximum wavelength of 259 nm.

  6. I see that the  molecular weight for Adenosine 5'-diphosphate (ADP) sodium salt, Product A2754, on the website does not include sodium, water and solvent content. Why is that?

    The amount of sodium, water and solvent for ADP sodium salt will vary from lot to lot.  The specific lot information can be found on the certificate of analysis located at our website. To obtain the "true" molecular weight (so that one can calculate the molarity of a solution), the sodium, water and solvent amount must be added to the molecular weight listed on the website.

  7. How do I find price and availability?

    There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

  8. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  9. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

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