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CN
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文件

A2383

Sigma-Aldrich

腺苷 5'-三磷酸 二钠盐 水合物

Grade I, ≥99%, from microbial

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别名:
ATP 二钠盐
经验公式（希尔记法）:
C10H14N5Na2O13P3 · xH2O
CAS号:
34369-07-8
分子量:
551.14 (anhydrous basis)
EC 号:
213-579-1
MDL编号:
MFCD00150755
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
24890481
NACRES:
NA.51

生物来源

microbial

质量水平

200

类型

Grade I

检测方案

≥99%

形式

powder

溶解性

H2O: 50 mg/mL

储存温度

−20°C

SMILES字符串

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

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应用

腺苷5′-三磷酸腺苷(ATP) 二钠盐水合物已用于：
  • 制备测定各种细菌培养物的三磷酸腺苷(ATP)标准溶液
  • 处理骨髓来源巨噬细胞 (BMDM)
  • 用作研究衣壳蛋白β亚基(β-COP)的无鸟嘌呤核苷酸污染制剂

生化/生理作用

P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物
腺苷5′-三磷酸((ATP)是体内能量储存和代谢的核心组分。ATP用于许多细胞过程，包括呼吸、生物合成反应、主动运输和迁移。ATP是许多参与信号传导的激酶以及生成二级信使环磷酸腺苷(cAMP)的腺苷酸环化酶的底物。ATP为驱动代谢泵提供代谢能。ATP在多种酶促反应中充当辅酶。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type N95 (US)

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Release of extracellular ATP by bacteria during growth
Mempin R, et al.
BMC Microbiology, 13(1), 301-301 (2013)
J G Donaldson et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(14), 6408-6412 (1992-07-15)
The coatomer is a cytosolic protein complex that reversibly associates with Golgi membranes and is implicated in modulating Golgi membrane transport. The association of beta-COP, a component of coatomer, with Golgi membranes is enhanced by guanosine 5'-[gamma-thio]triphosphate (GTP[gamma S]), a
Rui Nian et al.
Biotechnology progress, 25(4), 1078-1085 (2009-06-25)
The use of polyethylene glycol (PEG) as a refolding additive to a refolding cocktail comprising the molecular bichaperone ClpB and DnaKJE significantly enhances chaperone-mediated refolding of heat-denatured malate dehydrogenase (MDH). The critical factor to affect the refolding yield is the
Physiology, Adenosine Triphosphate (ATP)
NCBI Bookshelf null
Mass spectrometry and NMR spectroscopy based quantitative metabolomics
Proteomics. Clinical Applications (2020)
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