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Merck
CN

A2383

Sigma-Aldrich

腺苷 5'-三磷酸 二钠盐 水合物

Grade I, ≥99%, from microbial

别名:

ATP 二钠盐

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About This Item

经验公式(希尔记法):
C10H14N5Na2O13P3 · xH2O
CAS号:
分子量:
551.14 (anhydrous basis)
EC 号:
MDL编号:
UNSPSC代码:
41106305
eCl@ss:
32160414
PubChem化学物质编号:
NACRES:
NA.51

生物来源

microbial

质量水平

类型

Grade I

方案

≥99%

表单

powder

溶解性

H2O: 50 mg/mL

储存温度

−20°C

SMILES字符串

O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O

InChI

1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1

InChI key

NTBQNWBHIXNPRU-MSQVLRTGSA-L

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相关类别

应用

腺苷5′-三磷酸腺苷(ATP) 二钠盐水合物已用于:
  • 制备测定各种细菌培养物的三磷酸腺苷(ATP)标准溶液
  • 处理骨髓来源巨噬细胞 (BMDM)
  • 用作研究衣壳蛋白β亚基(β-COP)的无鸟嘌呤核苷酸污染制剂

生化/生理作用

P2 嘌呤受体激动剂。
P2 嘌呤能激动剂;增加 Ca2+-激活的 K+ 通道的活性;ATP-依赖酶系统的底物
腺苷5′-三磷酸((ATP)是体内能量储存和代谢的核心组分。ATP用于许多细胞过程,包括呼吸、生物合成反应、主动运输和迁移。ATP是许多参与信号传导的激酶以及生成二级信使环磷酸腺苷(cAMP)的腺苷酸环化酶的底物。ATP为驱动代谢泵提供代谢能。ATP在多种酶促反应中充当辅酶。

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Rui Nian et al.
Biotechnology progress, 25(4), 1078-1085 (2009-06-25)
The use of polyethylene glycol (PEG) as a refolding additive to a refolding cocktail comprising the molecular bichaperone ClpB and DnaKJE significantly enhances chaperone-mediated refolding of heat-denatured malate dehydrogenase (MDH). The critical factor to affect the refolding yield is the
Release of extracellular ATP by bacteria during growth
Mempin R, et al.
BMC Microbiology, 13(1), 301-301 (2013)
J G Donaldson et al.
Proceedings of the National Academy of Sciences of the United States of America, 89(14), 6408-6412 (1992-07-15)
The coatomer is a cytosolic protein complex that reversibly associates with Golgi membranes and is implicated in modulating Golgi membrane transport. The association of beta-COP, a component of coatomer, with Golgi membranes is enhanced by guanosine 5'-[gamma-thio]triphosphate (GTP[gamma S]), a
Physiology, Adenosine Triphosphate (ATP)
NCBI Bookshelf null
Mass spectrometry and NMR spectroscopy based quantitative metabolomics
Proteomics. Clinical Applications (2020)

商品

Learn about the four membrane-bound protein complexes that make up the electron transport chain metabolic pathway supplying energy as ATP for cellular respiration.

实验方案

Measure luciferase activity using a luminometer assay detecting light emission, with applications in ATP detection and genetic function reporting.

在测定己糖激酶活性时,使用了一种在340nm处的连续分光光度法进行测定。己糖激酶使用ATP作为磷酸的来源来催化D-己糖的磷酸化。

Measure hexokinase activity using a continuous spectrophotometric rate-determination assay at 340 nm, catalyzing D-hexose sugar phosphorylation using ATP.

Enzymatic assay of lipase type XIII from Pseudomonas sp. using a coupled enzyme system of glycerol kinase and glycerophosphate oxidase (EC 3.1.1.3)

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