A6419
腺苷 5′-三磷酸 二钠盐 水合物
microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)
别名:
ATP 二钠盐
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关于此项目
经验公式（希尔记法）:
C10H14N5Na2O13P3 · xH2O
化学文摘社编号:
分子量:
551.14 (anhydrous basis)
UNSPSC Code:
12352207
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.75
MDL number:
产品名称
腺苷 5′-三磷酸 二钠盐 水合物, microbial, BioReagent, suitable for cell culture, ≥99% (HPLC)
SMILES string
O.[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP(O)(=O)OP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
InChI
1S/C10H16N5O13P3.2Na.H2O/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;1H2/q;2*+1;/p-2/t4-,6-,7-,10-;;;/m1.../s1
InChI key
NTBQNWBHIXNPRU-MSQVLRTGSA-L
biological source
microbial
product line
BioReagent
assay
≥99% (HPLC)
form
powder
technique(s)
cell culture | mammalian: suitable
solubility
H2O: 50 mg/mL
storage temp.
−20°C
Quality Level
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Application
腺苷5′-三磷酸二钠盐水合物用于：
- 寄生物内CRISPR/Cas9质粒转换的转染组分
- 骨髓衍生巨噬细胞炎症激活分析
- 次级巨噬细胞
- 核酸合成
Biochem/physiol Actions
P2 嘌呤受体激动剂。
P2 嘌呤能激动剂；增加 Ca2+-激活的 K+ 通道的活性；ATP-依赖酶系统的底物
General description
腺苷5′-三磷酸（ATP）在生物过程，包括神经传递，信号传导，肌肉收缩和心脏功能中是最基础的物质。ATP是活系统主要能量来源。细胞在压力下释放ATP，在免疫应答中有重要作用。ATP从受伤的神经释放，随后断裂产生腺苷。ATP可用作麻醉和危重医学疼痛管理的治疗选择。ATP水平升高意味着细胞损伤和炎症。
存储类别
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type N95 (US)
Potential value of adenosine 5?-triphosphate (ATP) and adenosine in anaesthesia and intensive care medicine
Skrabanja ATP, et al.
British Journal of Anaesthesia, 94(5), 556-562 (2005)
Adenosine and its receptors as therapeutic targets: an overview
Sachdeva S and Gupta M
Saudi Pharmaceutical Journal : SPJ : The Official Publication of the Saudi Pharmaceutical Society, 21(3), 245-253 (2013)
Deuterated nucleotides as chemical probes of RNA structure: a detailed protocol for the enzymatic synthesis of a complete set of nucleotides specifically deuterated at ribose carbons
Tullius T, et al.
ScienceOpen Research (2018)
Effect of interleukin-31 on septic shock through regulating inflammasomes and interleukin-1beta
Gu X, et al.
Experimental and Therapeutic Medicine, 16(1), 171-177 (2018)
Extracellular ATP and adenosine: the Yin and Yang in immune responses?
Faas MM, et al.
Molecular Aspects of Medicine, 55(5), 9-19 (2017)
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