01930
腺苷 5′-单磷酸 二钠盐
≥99.0% (HPLC)
别名:
5′-AMP二钠盐,, 腺苷酸二钠盐, 5′-AMP-Na2
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关于此项目
经验公式（希尔记法）:
C10H12N5Na2O7P
化学文摘社编号:
分子量:
391.18
PubChem Substance ID:
eCl@ss:
32160414
UNSPSC Code:
41106305
NACRES:
NA.51
EC Number:
224-961-2
MDL number:
Beilstein/REAXYS Number:
3586732
产品名称
腺苷 5′-单磷酸 二钠盐, ≥99.0% (HPLC)
SMILES string
[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O
[Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])([O-])=O)[C@@H](O)[C@H]3O
InChI key
QGXLVXZRPRRCRP-IDIVVRGQSA-L
InChI
1S/C10H14N5O7P.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
biological source
microbial (Candida utilis)
synthetic
assay
≥99.0% (HPLC)
form
powder
optical activity
[α]20/D −43±2°, c = 1% in 0.5 M Na2HPO4 (dry matter)
impurities
≤26% water
Quality Level
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Application
5′-单磷酸腺苷二钠盐已用于：
- 作为可溶性有机磷（DOP）化合物，以研究在大肠杆菌裂解物中的水解速率
- 诱导Fura2成骨细胞（C2-OB）钙反应
- 在分离、培养和鉴定胶质瘤干细胞（GSC）的培养基中作为核苷酸代谢物
腺苷5′-一磷酸（5′-AMP）在自然界中具有许多用途。5′-AMP是一类蛋白激酶[AMP活化蛋白激酶（AMPK）]的激活剂。它可以用作多种酶的底物，如AMP-胸苷激酶(EC 2.7.1.114)、AMP脱氨酶(EC 3.5.4.6)和5′-核苷酸酶(EC 3.1.3.5)。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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The present study was conducted to estimate the effects of dietary carbohydrates on muscle quality and the underlying mechanisms. Six isonitrogenous and isolipidic diets were formulated to contain graded levels of carbohydrates (0%, 8%, 12%, 16%, 20% and 24%, respectively).
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Tsuchiya Y, Denison FC, et al.
Bioscience Reports, 32(2), 197-213 (2011)
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