所有图片(2)
About This Item
经验公式（希尔记法）:
C10H15N5O10P2 · 2C6H13N
CAS号:
分子量:
625.55
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
推荐产品
生物来源
bacterial
质量水平
方案
≥95% (HPLC)
表单
crystalline
溶解性
H2O: soluble, clear to slightly hazy, colorless to faintly yellow
储存温度
−20°C
SMILES字符串
NC1CCCCC1.NC2CCCCC2.Nc3ncnc4n(cnc34)[C@@H]5O[C@H](COP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]5O
InChI
1S/C10H15N5O10P2.2C6H13N/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;2*7-6-4-2-1-3-5-6/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);2*6H,1-5,7H2/t4-,6-,7-,10-;;/m1../s1
InChI key
SCOUEIPNDLFPCX-IDIVVRGQSA-N
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相关类别
应用
5′-二磷酸腺苷（ADP）是通过ATP合酶转化为ATP而参与能量储存和核酸代谢的腺嘌呤核苷酸。ADP通过其与ADP受体P2Y1、P2Y12和P2X1的相互作用影响血小板活化。 在通过ecto-ADP酶转化为腺苷后，通过腺苷受体抑制血小板活化。
腺苷-5′-二磷酸二环己胺盐已被用作发光测定（luminometry）中的标准品。它也已用于苏拉明抑制分析。
注意
稳定，不吸潮
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
The trypanocidal drug suramin and other trypan blue mimetics are inhibitors of pyruvate kinases and bind to the adenosine site
Morgan HP, et al.
The Journal of Biological Chemistry, 286(36), 31232-31240 (2011)
Effects of anticoagulants used during blood collection on human platelet function
May J A and Heptinstall S
Platelets and megakaryocytes, 3-11 (2004)
Sarah Jones et al.
British journal of haematology, 153(1), 83-91 (2011-02-22)
ADP is considered a weak platelet agonist due to the limited aggregation responses it induces in vitro at physiological concentrations of extracellular Ca(2+) [(Ca(2+) )(o) ]. Lowering [Ca(2+) ](o) paradoxically enhances ADP-evoked aggregation, an effect that has been attributed to
David Erlinge
Advances in pharmacology (San Diego, Calif.), 61, 417-439 (2011-05-19)
The purine- and pyrimidine-sensitive P2Y receptors belong to the large group of G-protein-coupled receptors that are the target of approximately one-third of the pharmaceutical drugs used in the clinic today. It is therefore not unexpected that the P2Y receptors could
David Iyú et al.
Arteriosclerosis, thrombosis, and vascular biology, 31(2), 416-422 (2010-11-26)
To investigate whether adenosine diphosphate (ADP)-derived adenosine might inhibit platelet aggregation, especially in the presence of a P2Y₁₂ antagonist, where the effects of ADP at the P2Y₁₂ receptor would be prevented. Platelet aggregation was measured in response to thrombin receptor
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