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主要文件

安全信息

60615

Sigma-Aldrich

硫酸卡那霉素

mixture of Kanamycin A (main component) and Kanamycin B and C

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选择尺寸

10 G
¥2,079.15
50 G
¥8,202.21
250 G
¥27,811.75

¥2,079.15


国内现货,预计发货时间2025年4月27日详情


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选择尺寸

变更视图
10 G
¥2,079.15
50 G
¥8,202.21
250 G
¥27,811.75

About This Item

线性分子式:
C18H36-37N4-5O10-11 · H2SO4
CAS号:
Beilstein:
3874279
MDL编号:
UNSPSC代码:
51281654
PubChem化学物质编号:
NACRES:
NA.85

¥2,079.15


国内现货,预计发货时间2025年4月27日详情


获取大包装报价

质量水平

表单

powder or crystals

效能

≥750 units per mg (calculated with reference to dried substance)

灼烧残渣

≤0.5% (as SO4)

缺失

≤1.5% loss on drying

颜色

white to off-white

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycobacteria
mycoplasma

作用机制

protein synthesis | interferes

SMILES字符串

OS(O)(=O)=O.NC[C@H]1O[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

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此商品
748847488551832
assay

≥99.0% (T)

assay

≥99.0% (T)

assay

≥97.0% (T)

assay

≥99.0% (T)

form

sheet

form

sheet

form

sheet

form

solid

suitability

corresponds to standard for RP gradient test, corresponds to standard for filter test

suitability

-

suitability

-

suitability

corresponds to standard for RP gradient test, corresponds to standard for filter test

technique(s)

ion pair chromatography: suitable

technique(s)

ion pair chromatography: suitable

technique(s)

-

technique(s)

ion pair chromatography: suitable

mol wt

234.29 g/mol

mol wt

234.29 g/mol

mol wt

-

mol wt

220.26 g/mol

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

≥300 °C (lit.)

mp

-

一般描述

Chemical structure: aminoglycoside

应用

Kanamycin sulfate is a broad spectrum aminoglycoside-antibiotic derived from Streptomyces kanamyceticus. It is used as an additive in culture media for the isolation of group D streptococci on Kanamycin Esculin Azide Agar and for selection of transformed plant cells containing the neomycin phosphotransferase on a kanamycin-medium.†† Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100 μg/mL.

生化/生理作用

Mode of Action: The product acts by binding to the 70S ribosomal subunit, inhibiting translocation and eliciting miscoding.

Mode of Resistance: Aminoglycoside-modifying enzymes (including acetyltransferase, phosphotransferase, nucleotidyltransferase) can alter this antibiotic, preventing its interaction with ribosomes.

Antimicrobial Spectrum: Kanamycin sulfate is effective against gram-negative and gram-postiive bacteria, and mycoplasma.

包装

5g, 25 g

注意

Solutions are stable at 37°C for approximately 5 days. Aqueous stock solutions can be stored at 2-8°C for long term storage.

制备说明

Kanamycin sulfate is soluble in water at 50 mg/mL, yielding a clear solution. It is practically insoluble in alcohol, acetone, chloroform, ether and ethyl acetate. A 1% solution in water has a pH of 6.5 to 8.5. Sterile solutions can be prepared by a sterile filtration, through a .2μm filter.

其他说明

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.Storage class (TRGS 510): Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

象形图

Health hazard

警示用语:

Danger

危险声明

危险分类

Repr. 1B

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品

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