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Merck
CN

P-075

普里米酮

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C12H14N2O2
化学文摘社编号:
125-33-7
分子量:
218.25
NACRES:
NA.24
UNSPSC Code:
41116107
EC Number:
200-659-6

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产品名称

普里米酮, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

InChI key

DQMZLTXERSFNPB-UHFFFAOYSA-N

InChI

1S/C12H14N2O2/c1-2-12(9-6-4-3-5-7-9)10(15)13-8-14-11(12)16/h3-7H,2,8H2,1H3,(H,13,15)(H,14,16)

SMILES string

CCC1(C(=O)NCNC1=O)c2ccccc2

grade

certified reference material

form

liquid

feature

Snap-N-Spike®/Snap-N-Shoot®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in methanol

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

forensics and toxicology

format

single component solution

storage temp.

−20°C

Quality Level

300

Gene Information

human ... GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), GABRD(2563), GABRE(2564), GABRG1(2565), GABRG2(2566), GABRG3(2567), GABRP(2568), GABRQ(55879), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335)

相关类别

Legal Information

Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Liskantin is a registered trademark of Desitin Arzneimittel GmbH
Mysoline is a registered trademark of Valeant Pharmaceuticals North America LLC

General description

Primidone, marketed as the barbiturate Mysoline®, Prysoline, or Liskantin®, is an anticonvulsant used in the treatment of partial and generalized seizures. This Certified Spiking Solution® is suitable for use in LC/MS or GC/MS applications in clinical toxicology or therapeutic drug monitoring to ensure patients remain within the drug′s therapeutic range.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

target_organs

Eyes,Central nervous system

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

49.5 °F - closed cup

flash_point_c

9.7 °C - closed cup

法规信息

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Susheela Rani et al.
Journal of separation science, 35(3), 359-366 (2012-01-20)
A method for the simultaneous determination of the antiepileptic drugs, phenobarbital (PHB), phenytoin (PTN), carbamazepine (CBZ), primidone (PRM) and oxcarbazepine (OXC) in human plasma and urine samples by using micro-extraction in a packed syringe as the sample preparation method connected
B Rezaei et al.
Talanta, 79(3), 669-675 (2009-07-07)
Application of electrospray ionization ion mobility spectrometry (ESI-IMS) as the detection technique for separation method based on molecular imprinted polymer (MIP) was investigated and evaluated. The method is exhaustively validated, including sensitivity, selectivity, recovery, reproducibility, and column capacity. The linear
Feng Chen et al.
Environmental pollution (Barking, Essex : 1987), 159(6), 1490-1498 (2011-04-12)
This study investigated the occurrence of 43 emerging contaminants including 9 endocrine-disrupting chemicals and 34 pharmaceuticals in three sites in Hebei Province, north China. Each site has a wastewater irrigated plot and a separate groundwater irrigated plot for comparison purpose.
Christopher G Favilla et al.
Parkinsonism & related disorders, 19(2), 171-175 (2012-10-16)
Many essential tremor patients continue to require tremor suppressing medications following deep brain stimulation. The true incidence of medication usage in the years following surgery remains unclear, and the use of medications has not been included in the post-operative analyses
Ulrike Hass et al.
Water research, 46(18), 6013-6022 (2012-09-13)
The occurrence and distribution of six psychoactive compounds (primidone, phenobarbital, oxazepam, diazepam, meprobamate, and pyrithyldione) and a metabolite of primidone (phenylethylmalonamide) were investigated in wastewater treatment plant (WWTP) effluents, surface water, groundwater of a bank filtration site, raw and final
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