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GABRB2

gamma-aminobutyric acid (GABA) A receptor, beta 2

别名:
物种:
UniProtKB ID:
基因ID:
  • Human(2561) Summary: The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion. [provided by RefSeq, Jul 2008]
  • Mouse(14401) gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
  • Rat(25451) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • sheep(100913155) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic guinea pig(100720162) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • naked mole-rat(101721168) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Zebrafish(336252) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • domestic cat(101094237) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • cow(540657) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Domestic Rabbit(100356357) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • Horse(100059608) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • chicken(414890) gamma-aminobutyric acid (GABA) A receptor, beta 2
  • dog(489146) gamma-aminobutyric acid (GABA) A receptor, beta 2

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Small Molecule - Agonist

货号
说明
物种
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
Piperidine-4-sulfonic acid, ,
物种
human
γ-氨基丁酸, ≥99%,
物种
human, rat
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
丙泊酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
地西泮, European Pharmacopoeia (EP) Reference Standard,
物种
human
Thiopental, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
SR-95531, ≥98% (HPLC), powder,
物种
human
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
Ganaxolone, solid, ≥98% (HPLC),
物种
human, mouse
丙泊酚, 97%,
物种
human
γ-氨基丁酸, ≥99%,
物种
human, rat

Antibodies

货号
说明
物种反应性
应用
抗GABA A受体β2,3链抗体,克隆BD17, clone BD17, Chemicon®, from mouse,
物种反应性
bovine, feline, human, monkey, mouse, rat
应用
immunohistochemistry
immunoprecipitation (IP)

western blot
抗-GABA A受体β2抗体,细胞质环, Chemicon®, from rabbit,
物种反应性
bovine, human, mouse, rat
应用
immunoprecipitation (IP)
western blot
Anti-GABRB2 Antibody, clone BD17 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
物种反应性
bovine, feline, human, monkey, mouse, rat
应用
immunofluorescence
immunohistochemistry

western blot
Anti-GABRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-GABA A Receptor beta 2 (GABRB2) Antibody, clone 6G9O8, Rabbit Monoclonal, ,
物种反应性
human, rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
(±)-Vigabatrin, ,
物种
human
丙泊酚, 97%,
物种
human
托吡酯, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
托吡酯, United States Pharmacopeia (USP) Reference Standard,
物种
human

Small Molecule - Ligand

货号
说明
物种
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting mouse Gabrb2,
物种
mouse
MISSION® esiRNA, targeting human GABRB2,
物种
human