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AB5561

抗-GABA A受体β2抗体，细胞质环

Chemicon®, from rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IP, WB
Citations:
14
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biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

rat, mouse, bovine, human

manufacturer/tradename

Chemicon®

technique(s)

immunoprecipitation (IP): suitable, western blot: suitable

NCBI accession no.

NM_000813.2, NM_021911.2

UniProt accession no.

P47870

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... GABRB2(2561)

Immunogen

来自大鼠GABAA受体β2亚基胞质环的MBP融合蛋白。

Application

抗GABA A受体β2抗体，细胞质环是用于IP&WB的针对GABA A受体β2的抗体。
蛋白质印迹：1：1,000

免疫沉淀：使用15 μg抗体，该抗体可免疫沉淀大鼠前脑（150μ L）十二烷基硫酸盐提取物中68%的全部GABAA受体。

最佳工作稀释度必须由最终用户进行确定。

Biochem/physiol Actions

GABAA受体β2亚基。该抗体对大鼠脑膜组分中的〜50至56kDa具有特异性。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

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Evangelos Sotiriou et al.
Journal of neuroscience research, 82(5), 690-700 (2005-11-08)
Recent data demonstrate weaker gamma-aminobutyric acid (GABA)-ergic inhibition in ventral (VH) compared with dorsal (DH) hippocampus. Therefore, we examined possible differences regarding the GABAA receptors between VH and DH as follows: 1) the expression of the GABAA receptor subunits (alpha1/2/4/5
GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors.
Ding, L; Feng, HJ; Macdonald, RL; Botzolakis, EJ; Hu, N; Gallagher, MJ
The Journal of Biological Chemistry null
Timothy A Warner et al.
Human molecular genetics, 25(15), 3192-3207 (2016-06-25)
Genetic epilepsy is a common disorder with phenotypic variation, but the basis for the variation is unknown. Comparing the molecular pathophysiology of mutations in the same epilepsy gene may provide mechanistic insights into the phenotypic heterogeneity. GABRG2 is an established
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全球贸易项目编号

货号GTIN
AB556104053252671500