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Merck
CN

GABRD

gamma-aminobutyric acid (GABA) A receptor, delta

别名:
EIG10, EJM7, GEFSP5
物种:
UniProtKB ID:
基因ID:
  • Human(2563) Summary: Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. The GABA-A receptor is generally pentameric and there are five types of subunits: alpha, beta, gamma, delta, and rho. This gene encodes the delta subunit. Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures, type 5. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]
  • Mouse(14403) gamma-aminobutyric acid (GABA) A receptor, subunit delta
  • Rat(29689) gamma-aminobutyric acid (GABA) A receptor, delta
  • Zebrafish(571422) gamma-aminobutyric acid (GABA) A receptor, delta
  • chicken(770710) gamma-aminobutyric acid (GABA) A receptor, delta
  • cow(508711) gamma-aminobutyric acid (GABA) A receptor, delta
  • dog(489609) gamma-aminobutyric acid (GABA) A receptor, delta
  • sheep(101122539) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic cat(101087589) gamma-aminobutyric acid (GABA) A receptor, delta
  • domestic guinea pig(100735228) gamma-aminobutyric acid (GABA) A receptor, delta
  • naked mole-rat(101700143) gamma-aminobutyric acid (GABA) A receptor, delta

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Small Molecule - Agonist

货号
说明
物种
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
丙泊酚, Pharmaceutical Secondary Standard; Certified Reference Material,
物种
human
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
普鲁泊福, European Pharmacopoeia (EP) Reference Standard,
物种
human
阿普唑仑, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
丙泊酚, 97%,
物种
human
阿坎酸钙, ≥98% (HPLC), powder,
物种
human
阿坎酸钙, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
物种
human

Antibodies

货号
说明
物种反应性
应用
Anti-GABRD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunohistochemistry
Anti-GABRD antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, human, mouse, rabbit
应用
immunohistochemistry
western blot

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human GABRD,
物种
human
MISSION® esiRNA, targeting mouse Gabrd,
物种
mouse