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Merck
CN

GABRA6

gamma-aminobutyric acid (GABA) A receptor, alpha 6

别名:
物种:
Human GABRA6 (2559), Mouse Gabra6 (14399), Rat Gabra6 (29708), dog GABRA6 (489145), domestic cat GABRA6 (101093992), cow GABRA6 (539194), sheep GABRA6 (101117503), Horse GABRA6 (100070890), naked mole-rat Gabra6 (101720123), domestic guinea pig Gabra6 (100720891)
UniProtKB ID:
Q16445, A8K096, Q4VAV2
基因ID:
  • Human(2559) Summary: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(14399) gamma-aminobutyric acid (GABA) A receptor, subunit alpha 6
  • Rat(29708) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • dog(489145) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic cat(101093992) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • cow(539194) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • sheep(101117503) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • Horse(100070890) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • naked mole-rat(101720123) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • domestic guinea pig(100720891) gamma-aminobutyric acid (GABA) A receptor, alpha 6
  • chicken(395931) gamma-aminobutyric acid (GABA) A receptor, alpha 6

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Small Molecule - Agonist

货号
说明
物种
T101
加波沙朵 盐酸盐, solid, ≥98% (HPLC),
物种
human
G019
蝇蕈醇 氢溴酸盐, ≥98% (HPLC), solid,
物种
human
P9159
Piperidine-4-sulfonic acid, ,
物种
human
A2129
γ-氨基丁酸, ≥99%,
物种
human, rat
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

Small Molecule - Allosteric Modulator

货号
说明
物种
1572503
普鲁泊福, United States Pharmacopeia (USP) Reference Standard,
物种
human
P-076
丙泊酚标准液 CRM 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
1661002
Thiopental, United States Pharmacopeia (USP) Reference Standard,
物种
human
Y0000016
普鲁泊福, European Pharmacopoeia (EP) Reference Standard,
物种
human
C2385000
氯硝西泮, European Pharmacopoeia (EP) Reference Standard,
物种
human

Small Molecule - Antagonist

货号
说明
物种
R109
Ro 15-4513, solid,
物种
rat, human
S106
SR-95531, ≥98% (HPLC), powder,
物种
human
1273808
Flumazenil, United States Pharmacopeia (USP) Reference Standard,
物种
human
G7795
Ganaxolone, ≥98% (HPLC), solid,
物种
human, mouse
D126608
丙泊酚, 97%,
物种
human

Antibodies

货号
说明
物种反应性
应用
AB5453
Anti-GABA A Receptor α6 Antibody, Chemicon®, from rabbit,
物种反应性
rat
应用
immunohistochemistry
western blot
G0295
Anti-GABAA Receptor (α6 subunit), Cytosolic Loop antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
rat
应用
western blot
G5544
Anti-GABAA Receptor (α6 subunit) antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
rat
应用
western blot

Small Molecule - Inhibitor

货号
说明
物种
N142
NO-711 hydrochloride, ≥98% (HPLC),
物种
human
V8261
(±)-Vigabatrin, ,
物种
human
D126608
丙泊酚, 97%,
物种
human
1672206
托吡酯, United States Pharmacopeia (USP) Reference Standard,
物种
human
T-039
Topiramate solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human

Small Molecule - Ligand

货号
说明
物种
B4388
2-溴-2-氯-1,1,1-三氟乙烷, ≥99%,
物种
human

esiRNA

货号
说明
物种
EHU000761
MISSION® esiRNA, targeting human GABRA6,
物种
human