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Merck
CN
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AB5453

Sigma-Aldrich

Anti-GABA A Receptor α6 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

rat

制造商/商品名称

Chemicon®

技术

immunohistochemistry: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

特异性

GABA A receptor alpha6 subunit. The apparent molecular mass of the alpha6 subunit in rat brain membrane fractions is 56-57 kDa. The antibody shows no reactivity in the forebrain of alpha6 knockout mice.

免疫原

MBP fusion protein from the cytosolic loop of rat GABA A receptor alpha6 subunit.

应用

Anti-GABA A Receptor α6 Antibody detects level of GABA A Receptor α6 & has been published & validated for use in IH & WB.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Western blot: 1:1,000

Immunopreciptation: The antibody will immunoprecipitate 53% of all GABA A receptors in sodium dodecylsulfate extracts of rat forebrains (150 μL) using 15 μg of antibody.

Optimal working dilutions must be determined by the end user.

外形

Affinity purified immunoglobulin in 10 mM HEPES, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.

储存及稳定性

Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2


分析证书(COA)

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James S Martenson et al.
eLife, 6 (2017-08-18)
GABAA receptor (GABAAR) pentamers are assembled from a pool of 19 subunits, and variety in subunit combinations diversifies GABAAR functions to tune brain activity. Pentamers with distinct subunit compositions localize differentially at synaptic and non-synaptic sites to mediate phasic and
Gili Ezra-Nevo et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(30), 6751-6765 (2018-06-24)
Corticotropin-releasing factor (CRF) and its type 1 receptor (CRFR1) play an important role in the responses to stressful challenges. Despite the well established expression of CRFR1 in granular cells (GrCs), its role in procedural motor performance and memory formation remains
Giovanna Ponti et al.
PloS one, 3(6), e2366-e2366 (2008-06-05)
Adult neurogenesis in mammals is restricted to some brain regions, in contrast with other vertebrates in which the genesis of new neurons is more widespread in different areas of the nervous system. In the mammalian cerebellum, neurogenesis is thought to

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