Skip to Content

Dear Customer:

The current international situation is complex and volatile, and uncertain tariff policies may potentially impact our product prices. Given these uncertainties, we value your understanding regarding order-related matters.

If you decide to place an order during this period, we reserve the right to adjust the price based on the evolving situation. We understand that market changes may cause inconvenience. We will negotiate with you if there’s a significant price fluctuation due to tariff policy changes before the order’s actual delivery, and in such cases we may adjust or cancel the order as necessary.

For important updates on recent policy changes, please click here for more details.

Merck
CN

SCN4A

sodium channel, voltage-gated, type IV, alpha subunit

Synonyms:
HOKPP2, HYKPP, HYPP, NAC1A, Na(V)1.4, Nav1.4, SkM1
Species:
Human SCN4A (6329), Mouse Scn4a (110880), Rat Scn4a (25722), chicken SCN4A (771297), domestic cat SCN4A (101098669), naked mole-rat Scn4a (101713228), cow SCN4A (517426), sheep SCN4A (101123056), dog SCN4A (610754), domestic guinea pig Scn4a (100717730)
UniProtKB ID:
P35499, Q15478, Q16447, Q7Z6B1
Gene ID:
  • Human(6329) Summary: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. It is expressed in skeletal muscle, and mutations in this gene have been linked to several myotonia and periodic paralysis disorders. [provided by RefSeq, Jul 2008]
  • Mouse(110880) sodium channel, voltage-gated, type IV, alpha
  • Rat(25722) sodium channel, voltage-gated, type IV, alpha subunit
  • chicken(771297) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic cat(101098669) sodium channel, voltage-gated, type IV, alpha subunit
  • naked mole-rat(101713228) sodium channel, voltage-gated, type IV, alpha subunit
  • cow(517426) sodium channel, voltage-gated, type IV, alpha subunit
  • sheep(101123056) sodium channel, voltage-gated, type IV, alpha subunit
  • dog(610754) sodium channel, voltage-gated, type IV, alpha subunit
  • domestic guinea pig(100717730) sodium channel, voltage-gated, type IV, alpha subunit
  • Horse(100049793) sodium channel, voltage-gated, type IV, alpha subunit

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
HPA053992
Anti-SCN4A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
S8809
Monoclonal Anti-Sodium Channel, Pan antibody produced in mouse, ~1 mg/mL, clone K58/35, purified immunoglobulin,
Species Reactivity
mammals
Application
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Blocker

Product Number
Description
Species
R6152
Ranolazine dihydrochloride, ≥98% (HPLC), powder,
Species
human
T7508
Tetracaine hydrochloride, ≥99%,
Species
human
P9879
Procaine hydrochloride, ≥97%,
Species
human
M2727
Mexiletine hydrochloride, powder,
Species
human
PHR1034
Lidocaine, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human

esiRNA

Product Number
Description
Species
EMU086881
MISSION® esiRNA, targeting mouse Scn4a,
Species
mouse
EHU155051
MISSION® esiRNA, targeting human SCN4A,
Species
human