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安全信息

L5647

Sigma-Aldrich

利多卡因 盐酸盐 一水合物

≥99% (HPLC), solid, Na⁺ channel blocker

别名:

2-二乙氨基-N-（2，6-二甲苯基）乙酰胺 盐酸盐 一水合物, 利多卡因 盐酸盐 一水合物, 赛洛卡因 盐酸盐 一水合物

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5 ML
¥1,446.06
15 ML
¥3,109.05

¥1,446.06

预计发货时间2025年7月21日详情

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5 ML
¥1,446.06
15 ML
¥3,109.05

About This Item

经验公式（希尔记法）:
C14H22N2O · HCl · H2O
CAS号:
6108-05-0
分子量:
288.81
EC 号:
200-803-8
MDL编号:
MFCD00150329
UNSPSC代码:
12352200
PubChem化学物质编号:
24277718
NACRES:
NA.77

¥1,446.06

预计发货时间2025年7月21日详情

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产品名称

利多卡因 盐酸盐 一水合物, solid

表单

solid

质量水平

200

颜色

white

溶解性

H2O: soluble

SMILES字符串

Cl[H].[H]O[H].CCN(CC)CC(=O)Nc1c(C)cccc1C

InChI

1S/C14H22N2O.ClH.H2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4;;/h7-9H,5-6,10H2,1-4H3,(H,15,17);1H;1H2

InChI key

YECIFGHRMFEPJK-UHFFFAOYSA-N

基因信息

human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

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此商品
C5338P7892GE17090601
N-Hydroxysuccinimidyl-Sepharose™ 4 Fast Flow matrix fast-flow highly cross-linked 4% beaded agarose

H8280

N-Hydroxysuccinimidyl-Sepharose™ 4 Fast Flow

Cyanogen bromide-activated-Sepharose™ 4 Fast Flow lyophilized powder

C5338

Cyanogen bromide-activated-Sepharose™ 4 Fast Flow

Phenyl-Sepharose CL-4B extent of labeling: ~40 μmol per mL

P7892

Phenyl-Sepharose CL-4B

NHS Act Sepharose™ 4 Fast Flow Cytiva 17-0906-01, pack of 25 mL

GE17090601

NHS Act Sepharose™ 4 Fast Flow

matrix active group

N-hydroxysuccinimide active ester

matrix active group

cyanate or related structures

matrix active group

-

matrix active group

-

form

isopropanol suspension

form

lyophilized powder

form

suspension

form

-

technique(s)

protein array: suitable

technique(s)

affinity chromatography: suitable

technique(s)

-

technique(s)

-

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-8°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

-

一般描述

Lidocaine hydrochloride monohydrate is a commonly used as local anesthetic in topical applications and oral mucosal biopsies. It has a short anesthetic half-life.[1]

应用

Lidocaine hydrochloride monohydrate has been used:
  • in the preparation of drug composite for the controlled delivery in vitro, evaluated by drug release profile in ultra-high performance liquid chromatography (UPLC) and as a reference standard for fourier transform infrared spectroscopy (FT-IR).[1]
  • to record dose dependent response of sodium voltage (Nav1.7) channels in the injection-molded polymer device.[2]
  • For inhibition of glial cells in brain tissue samples.[3]

生化/生理作用

Na+ 通道阻滞剂；IB 类抗心律失常药，在肠胃外给药后迅速吸收
Na+ 通道阻滞剂；IB 类抗心律失常药。

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险声明

H301

预防措施声明

P301 + P310 + P330

危险分类

Acute Tox. 3 Oral

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

法规信息

新产品
  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    0000416671
    0000416662
    0000416662
    0000416671
    0000411335

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    访问文档库

    K Yokawa et al.
    Annals of botany, 122(5), 747-756 (2017-12-14)
    Anaesthesia for medical purposes was introduced in the 19th century. However, the physiological mode of anaesthetic drug actions on the nervous system remains unclear. One of the remaining questions is how these different compounds, with no structural similarities and even
    Dennis R Sparta et al.
    Nature protocols, 7(1), 12-23 (2011-12-14)
    In vivo optogenetic strategies have redefined our ability to assay how neural circuits govern behavior. Although acutely implanted optical fibers have previously been used in such studies, long-term control over neuronal activity has been largely unachievable. Here we describe a
    Kristine von Krogh et al.
    Biology, 10(11) (2021-11-28)
    Zebrafish are often euthanized by overdose of anaesthesia. However, fish may have aversion towards some anaesthetics, and protocol efficacy varies between species. Using wild type adult Danio rerio, we assessed time to loss of opercular beat, righting, and startle reflexes
    Functionalized silver doped hydroxyapatite scaffolds for controlled simultaneous silver ion and drug delivery
    Dubnika A, et al.
    Ceramics International, 43(4), 3698-3705 (2017)
    Nienke van Staaveren et al.
    Scientific reports, 10(1), 12978-12978 (2020-08-02)
    The gut-microbiota-brain axis is implicated in the development of behavioural disorders in mammals. As such, its potential role in disruptive feather pecking (FP) in birds cannot be ignored. Birds with a higher propensity to perform FP have distinct microbiota profiles
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