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Merck
CN

SCN5A

sodium channel, voltage-gated, type V, alpha subunit

别名:
CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1
物种:
UniProtKB ID:
基因ID:
  • Human(6331) Summary: The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene are a cause of long QT syndrome type 3 (LQT3), an autosomal dominant cardiac disease. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(20271) sodium channel, voltage-gated, type V, alpha
  • Rat(25665) sodium channel, voltage-gated, type V, alpha subunit
  • Domestic Rabbit(100009516) sodium channel, voltage-gated, type V, alpha subunit
  • domestic guinea pig(100723340) sodium channel, voltage-gated, type V, alpha subunit
  • naked mole-rat(101710111) sodium channel, voltage-gated, type V, alpha subunit
  • domestic cat(101100994) sodium channel, voltage-gated, type V, alpha subunit
  • Horse(100034027) sodium channel, voltage-gated, type V, alpha subunit
  • cow(282061) sodium channel, voltage-gated, type V, alpha subunit
  • sheep(101111582) sodium channel, voltage-gated, type V, alpha subunit
  • chicken(395947) sodium channel, voltage-gated, type V, alpha subunit
  • dog(403497) sodium channel, voltage-gated, type V, alpha subunit

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Antibodies

货号
说明
物种反应性
应用
Anti-Sodium Channel Nav1.5 Antibody, pain, Chemicon®, from rabbit,
物种反应性
rat
应用
western blot
Anti-Sodium Channel NaV1.5 human antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
物种反应性
human
应用
western blot
Anti-SCN5A antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
应用
western blot
Anti-SCN5A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
物种反应性
human
应用
immunofluorescence
Anti-SCN5A (C-terminal) antibody produced in rabbit, affinity isolated antibody,
物种反应性
bovine, canine, guinea pig, horse, human, mouse, rat
应用
immunohistochemistry
western blot

Small Molecule - Blocker

货号
说明
物种
氟卡尼 乙酸盐, ,
物种
human
(±)-Flecainide solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物种
human
氟卡尼 乙酸盐, United States Pharmacopeia (USP) Reference Standard,
物种
human
氟卡尼 乙酸盐, European Pharmacopoeia (EP) Reference Standard,
物种
human
氟卡尼 乙酸盐, British Pharmacopoeia (BP) Reference Standard,
物种
human

Small Molecule - Ligand

货号
说明
物种
拉莫三嗪, ≥98%, powder,
物种
rat, human

esiRNA

货号
说明
物种
MISSION® esiRNA, targeting human SCN5A,
物种
human