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Merck
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安全信息

F-017

Supelco

(±)-Flecainide solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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1 ML
¥613.25

¥613.25

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变更视图
1 ML
¥613.25

About This Item

经验公式（希尔记法）:
C17H20F6N2O3
CAS号:
54143-55-4
分子量:
414.34
EC 号:
200-659-6
MDL编号:
MFCD00864713
UNSPSC代码:
41116107
PubChem化学物质编号:
329799633
NACRES:
NA.24

¥613.25

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获取大包装报价

等级

certified reference material

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

包装形式

single component solution

储存温度

−20°C

相关类别

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(±)-Flecainide solution 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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(±)-Flecainide solution

三唑仑标准液 溶液 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

T910

三唑仑标准液 溶液

盐酸氟奋乃静标准液 二盐酸盐 溶液 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®

F903

盐酸氟奋乃静标准液 二盐酸盐 溶液

普里米酮 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

P075

普里米酮

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

technique(s)

gas chromatography (GC): suitable, liquid chromatography (LC): suitable

form

liquid

form

liquid

form

liquid

form

liquid

Quality Level

300

Quality Level

300

Quality Level

300

Quality Level

300

grade

certified reference material

grade

certified reference material

grade

certified reference material

grade

certified reference material

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

Flecainide, marketed under trade names such as Almarytm, Apocard, Ecrinal®, and Flécaine, is a class Ic antiarrhythmic drug used to prevent and treat a variety of cardiac arrhythmias. This Certified Spiking Solution® is suitable for use as a starting material in the preparation of calibrators, controls, or linearity standards in flecainide therapeutic drug monitoring methods by LC/MS or LC that ensure patients remain within the drug′s narrow therapeutic range.

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Ecrinal is a registered trademark of Laboratoires Asepta Corporation Monaco
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

危险化学品

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number

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    Nian Liu et al.
    Trends in cardiovascular medicine, 22(2), 35-39 (2012-08-08)
    Recent studies have shown that flecainide may be an effective therapy to prevent life-threatening arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia. Several hypotheses have been advanced to explain the antiarrhythmic mechanism of flecainide, including Na(+) channel blockade and a
    Lovely Chhabra et al.
    Indian heart journal, 64(4), 404-407 (2012-08-30)
    Flecainide (a class 1c antiarrhythmic) produces a dose-dependent decrease in intracardiac conduction. Its well known common electrocardiographic effects are prolongation of PR and QT intervals and the QRS complex duration. We report a case of flecainide toxicity in an elderly
    Heather Ellsworth et al.
    Pacing and clinical electrophysiology : PACE, 36(3), e87-e89 (2012-08-14)
    Flecainide is a Vaughan Williams Class Ic antidysrhythmic associated with PR, QRS, and QTc prolongation on the electrocardiogram and development of life-threatening cardiac toxicity in overdose. The cornerstone of treatment is fluid resuscitation and the administration of magnesium and sodium
    Kosuke Doki et al.
    Pharmacogenetics and genomics, 22(11), 777-783 (2012-09-04)
    To investigate the association between age-related decline in flecainide clearance and CYP2D6 genotype, we conducted a population pharmacokinetic analysis of flecainide using routine therapeutic drug monitoring data. Population pharmacokinetic analysis was performed on retrospective data from 163 genotyped patients treated
    [Flecainide intoxication].
    Santiago Nogué et al.
    Medicina clinica, 140(1), 46-46 (2012-10-03)
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