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此商品 | FD2000S | FD40S | FD250S |
|---|---|---|---|
| biological source synthetic | biological source synthetic (organic) | biological source synthetic (organic) | biological source bacterial (Leuconostoc mesenteroides) |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 200 |
| form powder or crystals | form powder | form powder | form powder |
| conjugate FITC conjugate | conjugate FITC conjugate | conjugate FITC conjugate | conjugate FITC conjugate |
| mol wt average mol wt 2,000,000 | mol wt average mol wt 2,000,000 | mol wt average mol wt 40,000 | mol wt average mol wt 250,000 |
| extent of labeling 0.001-0.020 mol FITC per mol glucose (substitution) | extent of labeling 0.003-0.020 mol FITC per mol glucose | extent of labeling 0.003-0.020 mol FITC per mol glucose | extent of labeling 0.003-0.020 mol FITC per mol glucose |
应用
L-萝卜硫素可用于研究小鼠原代前脂肪细胞6和小鼠巨噬细胞RAW 264.7细胞系 中Nrf2介导的信号转导。7
生化/生理作用
L-萝卜硫素是II期解毒酶的有效选择性诱导剂，且具有抗癌特性。在十字花科蔬菜（包括西兰花）中发现的有机硫化合物。
萝卜硫素是十字花科蔬菜中的一种抗癌、抗微生物和抗糖尿病化合物。3,4 它可诱导产生解毒酶，例如引起异生素转化的醌还原酶和谷胱甘肽S-转移酶。萝卜硫素还可增加肿瘤抑制蛋白的转录并抑制组蛋白脱乙酰酶的活性。它通过抑制LPS介导的iNOS、COX-2、IL-1β和TNF-α.的表达来调节炎症反应。3,5
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Valeria Capurro et al.
PloS one, 8(2), e56870-e56870 (2013-02-27)
Alzheimer's disease (AD) is characterized by progressive loss of cognitive function, dementia and altered behavior. Over 30 million people worldwide suffer from AD and available therapies are still palliative rather than curative. Recently, Memoquin (MQ), a quinone-bearing polyamine compound, has
Tiziana Latronico et al.
Inflammopharmacology, 29(2), 561-571 (2020-11-17)
Isothiocyanates (ITCs), present as glucosinolate precursors in cruciferous vegetables, have shown anti-inflammatory, antioxidant and anticarcinogenic activities. Here, we compared the effects of three different ITCs on ROS production and on the expression of matrix metalloproteinase (MMP)-2 and -9, which represent
Pengfei Liu et al.
Redox biology, 38, 101766-101766 (2020-10-31)
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible disease characterized by an increase in differentiation of fibroblasts to myofibroblasts and excessive accumulation of extracellular matrix in lung tissue. Pharmacological activation of NRF2 has proved to be a valuable antifibrotic
Mohammed Ali Selo et al.
Frontiers in bioengineering and biotechnology, 8, 1030-1030 (2020-10-06)
Multidrug resistance-associated protein-1 (MRP1/ABCC1) is highly expressed in human lung tissues. Recent studies suggest that it significantly affects the pulmonary disposition of its substrates, both after pulmonary and systemic administration. To better understand the molecular mechanisms involved, we studied the
Eugene Y H Yeung et al.
Drug metabolism and disposition: the biological fate of chemicals, 36(11), 2270-2276 (2008-08-30)
Pregnane X receptor (PXR; NR1I2) is a ligand-activated transcription factor that plays a role not only in drug metabolism and transport but also in various other biological processes. Ginkgo biloba is a herbal medicine commonly used to manage memory impairment.
商品
DISCOVER Bioactive Small Molecules for Nitric Oxide & Cell Stress Research
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