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生物来源
synthetic (organic)
质量水平
偶联物
FITC conjugate
表单
powder
分子量
average mol wt 40,000
标记范围
0.003-0.020 mol FITC per mol glucose
颜色
yellow to dark orange
溶解性
H2O: soluble 25 mg/mL, clear to slightly hazy, yellow to deep orange
储存温度
2-8°C
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相关类别
一般描述
葡聚糖是葡萄糖酐聚合物。由大约95%的α-D-(166)键组成。剩余的（163）键作为葡聚糖的分支。 天然葡聚糖的分子量(MW)经证实在 900 万至 5 亿的范围内。FITC-葡聚糖的最大激发波长为 490nm。它的 pH 范围为 5 至 9。
应用
异硫氰酸荧光素-葡聚糖（FITC-右旋糖酐，荧光素右旋糖酐，FITC）用于以下过程：
- 荧光素-葡聚糖显微镜。
- 评估多形核白细胞α防御素表达转基因小鼠体内肺血管的通透性。
- 通过流式细胞术定量细胞吞噬能力。
- 标记α乳白蛋白和脱氧核糖核酸酶。
用异硫氰酸荧光素标记的葡聚糖可用于动物的灌注研究。
联系
与 FD-40 类似，但由 Sigma 生产。
制备说明
Sigma 通常以 25mg/ml 或更高的浓度测试 FITC 葡聚糖在水中的溶解度。 溶液应避光。 在体内，FITC-葡聚糖稳定超过 24 小时。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Kristina Krempaska et al.
Respiratory research, 21(1), 25-25 (2020-01-17)
Idiopathic pulmonary fibrosis (IPF) is a chronic fatal lung disease without a cure and new drug strategies are urgently needed. Differences in behavior between diseased and healthy cells are well known and drug response can be different between cells isolated
The structure of NRRL B-512F dextran, methylation studies.
Van Cleve JW, Schacfer WC and Rist CE
Journal of the American Chemical Society, 4435 - 4438 null
Yun Mi Lee et al.
Journal of diabetes research, 2013, 245271-245271 (2013-12-29)
Retinal pathogenic angiogenesis in the eyes is a causative factor in retinopathy of prematurity, diabetic retinopathy, and age-related macular degeneration. This study was designed to examine the pathogenic role of the high-mobility group box-1 (HMGB1) protein and the inhibitory effect
Erika M J Siren et al.
Scientific reports, 8(1), 7581-7581 (2018-05-17)
Here we present a simple technique for re-directing reactions on the cell surface to the outermost region of the glycocalyx. Macromolecular crowding with inert polymers was utilized to reversibly alter the accessibility of glycocalyx proteoglycans toward cell-surface reactive probes allowing
Molecular weight, molecular-weight distribution and molecular size of native dextran.
AROND L H and H P FRANK
The Journal of Physical Chemistry, 953 - 957 (1954)
相关内容
Dextran is a polymer of anhydroglucose. It is composed of approximately 95% alpha-D-(166) linkages. The remaining (163) linkages account for the branching of dextran.
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