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质量水平
方案
≥97% (NMR)
表单
liquid
颜色
colorless to yellow
储存温度
-10 to -25°C
SMILES字符串
[S](=O)(CCCN=C=S)C
InChI key
LELAOEBVZLPXAZ-UHFFFAOYSA-N
生化/生理作用
Iberin is a natural isothiocyanates from cruciferous vegetables (cabbage, red cabbage, horseradish) that potently inhibits toll-like receptors (TLRs) signaling. Iberin covalently binds to TLR4 and TLR2, which inhibits TLR dimerization. Iberin exhibits potent antioxidant, anticancer, and antimicrobial activities. It is quorum-sensing inhibitor (QSI) of the bacterial pathogen Pseudomonas aeruginosa through downregulation of the Gac/Rsm QS network.
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
从最新的版本中选择一种:
Composition of the Gut Microbiome Influences Production of Sulforaphane-Nitrile and Iberin-Nitrile from Glucosinolates in Broccoli Sprouts
Nutrients, 13(9), 3013-3013 (2021)
Comparative systems biology analysis to study the mode of action of the isothiocyanate compound Iberin on Pseudomonas aeruginosa
Antimicrobial Agents and Chemotherapy, 58(11), 6648-6659 (2014)
Journal of microbiology and biotechnology, 26(12), 2036-2042 (2016-09-03)
We evaluated the potentials of 10 isothiocyanates (ITCs) from cruciferous vegetables and radish root hydrolysate for inhibiting the growth of oral pathogens, with an emphasis on assessing any structure-function relationship. Structural differences in ITCs impacted their antimicrobial activities against oral
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