产品线
BioChemika
等级
puriss. p.a.
检测方案
≥98.0% (HPLC)
浓度
10.0-11.0 mmol/L (UV)
技术
MALDI-MS: suitable
杂质
≤1.5% ddNDP (HPLC)
适用性
corresponds for UV test
储存温度
−20°C
SMILES字符串
[Na+].CC1=CN([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O
InChI
1S/C10H17N2O13P3.Na/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17;/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17);/q;+1/p-1/t7-,8+;/m0./s1
InChI key
QJSZKDPCBDXBCK-KZYPOYLOSA-M
一般描述
3′-Deoxythymidine 5′-triphosphate sodium (ddTTP) is a sugar-modified dTTP analogue which is selective inhibitor of HIV-associated reverse transcriptase (HIV-RT). It is also seen to inhibit the activity of DNA polymerase α.
包装
packaging : 1 μmol (approx. 91-100 μL)
替代产品
相关产品
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
Kevin A Fiala et al.
Nucleic acids research, 36(6), 1990-2001 (2008-02-16)
Our previous publication shows that Sulfolobus solfataricus Dpo4 utilizes an 'induced-fit' mechanism to select correct incoming nucleotides at 37 degrees C. Here, we provide a comprehensive report elucidating the kinetic mechanism of a DNA polymerase at a reaction temperature higher
Inhibition of the activity of DNA polymerase alpha by 2',3'-dideoxythymidine 5'-triphosphate.
K Ono et al.
Biochemical and biophysical research communications, 88(4), 1255-1262 (1979-06-27)
Sascha Tierling et al.
Epigenetics & chromatin, 3(1), 12-12 (2010-06-08)
DNA methylation changes are widely used as early molecular markers in cancer detection. Sensitive detection and classification of rare methylation changes in DNA extracted from circulating body fluids or complex tissue samples is crucial for the understanding of tumor etiology
Sylvia Steininger et al.
Nucleic acids research, 38(6), 1853-1865 (2009-12-31)
The Mre11/Rad50/Xrs2 (MRX) complex in Saccharomyces cerevisiae has well-characterized functions in DNA double-strand break processing, checkpoint activation, telomere length maintenance and meiosis. In this study, we demonstrate an involvement of the complex in the base excision repair (BER) pathway. We
Elena N Ilina et al.
Frontiers in microbiology, 4, 186-186 (2013-07-13)
Spectinomycin remains a useful reserve option for therapy of gonorrhea. The emergence of multidrug-resistant Neisseria gonorrhoeae strains with decreased susceptibility to cefixime and to ceftriaxone makes it the only medicine still effective for treatment of gonorrhea infection in analogous cases.
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门