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主要文件

42597

Supelco

3′-脱氧胸苷 5′-三磷酸 钠盐 溶液

BioChemika, puriss. p.a., suitable for MALDI-MS, ≥98.0% (HPLC)

别名:

2′,3′-二脱氧胸苷 5′-三磷酸, ddTTP

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5 G
¥897.27
25 G
¥1,463.25

¥897.27


国内现货,预计发货时间2025年4月25日详情


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5 G
¥897.27
25 G
¥1,463.25

About This Item

经验公式(希尔记法):
C10H16N2NaO13P3
分子量:
488.15
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:

¥897.27


国内现货,预计发货时间2025年4月25日详情


获取大包装报价

产品线

BioChemika

等级

puriss. p.a.

方案

≥98.0% (HPLC)

浓度

10.0-11.0 mmol/L (UV)

技术

MALDI-MS: suitable

杂质

≤1.5% ddNDP (HPLC)

适用性

corresponds for UV test

储存温度

−20°C

SMILES字符串

[Na+].CC1=CN([C@H]2CC[C@@H](COP([O-])(=O)OP(O)(=O)OP(O)(O)=O)O2)C(=O)NC1=O

InChI

1S/C10H17N2O13P3.Na/c1-6-4-12(10(14)11-9(6)13)8-3-2-7(23-8)5-22-27(18,19)25-28(20,21)24-26(15,16)17;/h4,7-8H,2-3,5H2,1H3,(H,18,19)(H,20,21)(H,11,13,14)(H2,15,16,17);/q;+1/p-1/t7-,8+;/m0./s1

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FHIFINROEHIFIPROEHIFIPNRO
technique(s)

PCR: suitable

technique(s)

PCR: suitable

technique(s)

PCR: suitable

technique(s)

PCR: suitable

usage

sufficient for ≤1,000 reactions (03553361001)

usage

sufficient for ≤200 reactions (04738292001), sufficient for ≤50 reactions (04738284001)

usage

sufficient for ≤2,500 reactions (03300234001), sufficient for 2500 reactions, sufficient for ≤500 reactions (03300226001), sufficient for 500 reactions

usage

sufficient for ≤125 reactions (04743725001), sufficient for ≤500 reactions (04743733001)

feature

High Fidelity PCR

feature

-

feature

High Fidelity PCR, dNTPs included: no, hotstart: no

feature

High Fidelity PCR, dNTPs included, hotstart: no

packaging

pkg of 2,500 U (03553361001 [10 x 250 U])

packaging

pkg of 125 U (04738284001), pkg of 500 U (04738292001 [2 x 250 U])

packaging

pkg of 2,500 U (03300234001 [10x250 U]), pkg of 500 U (03300226001 [2x250 U])

packaging

pkg of 125 U (04743725001), pkg of 500 U (04743733001 [2x250 U])

manufacturer/tradename

Roche

manufacturer/tradename

Roche

manufacturer/tradename

Roche

manufacturer/tradename

Roche

concentration

5 unit/μL

concentration

-

concentration

-

concentration

50 U/mL (working concentration)

一般描述

3′-Deoxythymidine 5′-triphosphate sodium (ddTTP) is a sugar-modified dTTP analogue which is selective inhibitor of HIV-associated reverse transcriptase (HIV-RT).[1] It is also seen to inhibit the activity of DNA polymerase α.[2]

包装

packaging : 1 μmol (approx. 91-100 μL)

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说明
价格

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说明
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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


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    Nucleic acids research, 38(6), 1853-1865 (2009-12-31)
    The Mre11/Rad50/Xrs2 (MRX) complex in Saccharomyces cerevisiae has well-characterized functions in DNA double-strand break processing, checkpoint activation, telomere length maintenance and meiosis. In this study, we demonstrate an involvement of the complex in the base excision repair (BER) pathway. We
    Elena N Ilina et al.
    Frontiers in microbiology, 4, 186-186 (2013-07-13)
    Spectinomycin remains a useful reserve option for therapy of gonorrhea. The emergence of multidrug-resistant Neisseria gonorrhoeae strains with decreased susceptibility to cefixime and to ceftriaxone makes it the only medicine still effective for treatment of gonorrhea infection in analogous cases.
    Sascha Tierling et al.
    Epigenetics & chromatin, 3(1), 12-12 (2010-06-08)
    DNA methylation changes are widely used as early molecular markers in cancer detection. Sensitive detection and classification of rare methylation changes in DNA extracted from circulating body fluids or complex tissue samples is crucial for the understanding of tumor etiology
    Inhibition of the activity of DNA polymerase alpha by 2',3'-dideoxythymidine 5'-triphosphate.
    K Ono et al.
    Biochemical and biophysical research communications, 88(4), 1255-1262 (1979-06-27)
    Kevin A Fiala et al.
    Nucleic acids research, 36(6), 1990-2001 (2008-02-16)
    Our previous publication shows that Sulfolobus solfataricus Dpo4 utilizes an 'induced-fit' mechanism to select correct incoming nucleotides at 37 degrees C. Here, we provide a comprehensive report elucidating the kinetic mechanism of a DNA polymerase at a reaction temperature higher

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