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Merck
CN

38419

Supelco

α-Cyano-2,3,4,5,6-pentafluorocinnamic acid

matrix substance for MALDI-MS, ≥95.0% (HPLC)

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别名:
2-Cyano-3-(2,3,4,5,6-pentafluorophenyl)-2-propenoic acid, PentaFCCA
经验公式(希尔记法):
C10H2F5NO2
分子量:
263.12
Beilstein:
22870656
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:

等级

matrix substance for MALDI-MS

质量水平

检测方案

≥95.0% (HPLC)

分析物功能类别

drugs of abuse, ionic liquids (quantification)

分析物化学类别

chlorinated lipids, lipids, peptides, phospholipids, phosphopeptides

技术

collision-induced dissociation MS/MS (CID-MS/MS): suitable
matrix-enhanced secondary ion MS (ME-SIMS): suitable

溶解性

methanol: 100 mg/10 mL, clear, colorless to light yellow

SMILES字符串

OC(/C(C#N)=C/C1=C(F)C(F)=C(F)C(F)=C1F)=O

InChI

1S/C10H2F5NO2/c11-5-4(1-3(2-16)10(17)18)6(12)8(14)9(15)7(5)13/h1H,(H,17,18)/b3-1+

InChI key

LYNQRDIQUFMLTI-HNQUOIGGSA-N

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Warning

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Thorsten Jaskolla et al.
Journal of the American Society for Mass Spectrometry, 20(5), 867-874 (2009-02-10)
Phosphatidylethanolamines (PEs) are abundant lipid constituents of the cellular membrane. The amino group of PEs exhibits high reactivity with hypochlorous acid that is generated under inflammatory conditions in vivo. The analysis of the resulting PE mono- and dichloramines is of
Dimitrios G Papasotiriou et al.
Journal of proteome research, 9(5), 2619-2629 (2010-04-07)
Peptide Mass Fingerprinting (PMF) of tryptically in-gel digested samples is a well-established protein identification technique for MALDI mass spectrometry but an in-depth PMF evaluation for in-gel digestions of less specific enzymes is still missing. This study demonstrates that the MALDI-LTQ-Orbitrap
Marcel Wiegelmann et al.
Analytical and bioanalytical chemistry, 405(22), 6925-6932 (2012-10-16)
A high analytical sensitivity in ultraviolet matrix-assisted laser desorption ionization mass spectrometry (MALDI-MS) is only achieved if the laser wavelength corresponds to a high optical absorption of the matrix. Laser fluence and the physicochemical properties of the compounds, e.g., the
Mark W Towers et al.
Journal of proteome research, 9(4), 1931-1940 (2010-02-13)
Matrix-assisted laser desorption/ionization (MALDI) is a key ionization technique in mass spectrometry (MS) for the analysis of labile macromolecules. An important area of study and improvements in relation to MALDI and its application in high-sensitivity MS is that of matrix
Jens Soltwisch et al.
Journal of the American Society for Mass Spectrometry, 24(10), 1477-1488 (2013-08-15)
The success of matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) as a widely employed analytical tool in the biomolecular sciences builds strongly on an effective laser-material interaction that is resulting in a soft co-desorption and ionization of matrix and imbedded biomolecules.

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