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39468

α-氰基-4-羟基肉桂酸

Name: α-氰基-4-羟基肉桂酸
Brand: SIAL

matrix substance for MALDI-MS, Ultra pure

别名:

α-CCA, α-CHCA, α-氰基, 4-HCCA, ACCA

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About This Item

线性分子式:

HOC₆H₄CH=C(CN)CO₂H

CAS号:

28166-41-8

分子量:

189.17

Beilstein:

3271427

EC 号:

248-879-1

MDL编号:

MFCD00004204

UNSPSC代码:

41116105

PubChem化学物质编号:

329755873

NACRES:

NA.21

等级

matrix substance for MALDI-MS

质量水平

100

形式

solid

分析物化学类别

glycans, peptides, proteins

技术

MALDI-MS: suitable

mp

245-250 °C (lit.)
245-250 °C

溶解性

methanol: 10 mg/mL, clear

痕量阳离子

Al: ≤1 mg/kg
Ba: ≤1 mg/kg
Ca: ≤1 mg/kg
Cd: ≤1 mg/kg
Co: ≤1 mg/kg
Cr: ≤1 mg/kg
Cu: ≤1 mg/kg
Fe: ≤1 mg/kg
K: ≤1 mg/kg
Li: ≤1 mg/kg
Mg: ≤1 mg/kg
Mn: ≤1 mg/kg
Na: ≤1 mg/kg
Ni: ≤1 mg/kg
Pb: ≤1 mg/kg
Sr: ≤1 mg/kg
Zn: ≤1 mg/kg

储存温度

2-8°C

SMILES字符串

OC(=O)\C(=C\c1ccc(O)cc1)C#N

InChI

1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+

InChI key

AFVLVVWMAFSXCK-VMPITWQZSA-N

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一般描述

α-氰基-4-羟基肉桂酸（α-CHCA）起基质的作用，有助于在基质辅助激光解吸/电离（MALDI）飞行时间（TOF）质谱仪中促进蛋白质和肽的电离。

应用

它被用作基质，用于改善 MALDI-TOF 上低浓度蛋白质消化物的检测。

警示用语：

Warning

危险声明

H317

预防措施声明

P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364

危险分类

Skin Sens. 1B

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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分析证书(COA)

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D(4)-α-Cyano-4-hydroxycinnamic acid (D(4)-CHCA) has been synthesized for use as a matrix for matrix-assisted laser desorption ionization-mass spectrometry (MALDI-MS) and MALDI-MS imaging (MSI) of small molecule drugs and endogenous compounds. MALDI-MS analysis of small molecules has historically been hindered by interference

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Ultra-Pure MALDI Matrices

One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient.

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