Detergent Screening Kit for crystallization

Similar to the Additive Screening Kit, this kit provides a range of detergents, that may be used for optimization. Detergents often interfere with the crystallization process. They are used to influence hydrophobic sample-sample interactions which may cause non-specific aggregation. On the other hand they can also influence the structure of water. The use of detergents is typically required for crystallization of membrane proteins or other proteins, if non-specific aggregation is suspected.

The detergent kit includes 48 defined detergents, that are pre-formulated for ease of use. The concentration of each detergent solution is adjusted to the 10-fold value of critical micelle concentration. The kit includes 100 μl of each pre-formulated detergent.