19899
CHAPS 100 mM 溶液
别名:
CHAPS 溶液
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关于此项目
经验公式（希尔记法）:
C32H58N2O7S
化学文摘社编号:
分子量:
614.88
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12161902
MDL number:
InChI
1S/C32H58N2O7S/c1-21(8-11-29(38)33-14-6-15-34(4,5)16-7-17-42(39,40)41)24-9-10-25-30-26(20-28(37)32(24,25)3)31(2)13-12-23(35)18-22(31)19-27(30)36/h21-28,30,35-37H,6-20H2,1-5H3,(H-,33,38,39,40,41)/t21-,22?,23-,24-,25+,26+,27-,28+,30+,31+,32-/m1/s1
SMILES string
C[C@H](CCC(=O)NCCC[N+](C)(C)CCCS([O-])(=O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)CC4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InChI key
UMCMPZBLKLEWAF-RFCNGIAKSA-N
description
zwitterionic
form
liquid
mol wt
614.88 g/mol
concentration
100 mM in H2O
technique(s)
protein quantification: suitable
CMC
8 mM
transition temp
cloud point >100 °C
density
1.01 g/mL at 20 °C
storage temp.
2-8°C
Quality Level
Application
CHAPS 100 mM 溶液可用作裂解缓冲液的成分，用于提取山羊子宫内膜上皮细胞（EEC）和肝组织的蛋白质。
Biochem/physiol Actions
3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）具有硫代甜菜碱型表面活性剂和胆汁盐的特性。它参与蛋白质组学分析用蛋白质的提取过程，并使膜蛋白重建进入脂质囊泡内部（蛋白脂质体）。CHAPS被广泛应用于生物化学领域膜蛋白和受体的分离和纯化。由于其生物相容性、无电荷特性、非变性和非聚集特性，它可用于药物和医学领域。
General description
3-[（3-胆固醇氨丙基）二甲基氨基]-1-丙磺酸（CHAPS）是一种生物相容性表面活性剂。它是胆酸的衍生物，包含疏水的胆固醇样骨架，具有三个羟基和一个两性离子脂肪族尾。
存储类别
12 - Non Combustible Liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves
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Applied biochemistry and biotechnology, 182(4), 1444-1457 (2017-02-01)
Pseudomonas aeruginosa biofilm-related infections are the major cause of premature death in cystic fibrosis patients. Strategies to induce biofilm dispersal are of interest, because of their potential in preventing biofilm-related infections. Our previous work demonstrated that n-butanolic Cyclamen coum extract
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