生物来源
goat
质量水平
偶联物
peroxidase conjugate
抗体形式
F(ab′)2 fragment of affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
种属反应性
mouse
制造商/商品名称
Chemicon®
浓度
0.8 mg/mL
技术
ELISA: suitable
western blot: suitable
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
免疫球蛋白G（IgG）是人血清中最丰富的免疫球蛋白。IgM 占到了总血清免疫球蛋白的5-10%。这些免疫球蛋白包含四条多肽链，包括两条重链（H）和两条轻链（L）。这些多肽链通过二硫键相互连接。IgM是脊椎动物中高度保守的抗体。IgM以五聚体的形式存在。IgG和IgM都由B细胞分泌。
应用
山羊抗小鼠IgG& IgM抗体（HRP偶联物）已用于蛋白质印迹（1：400）和免疫荧光（1：500）。
生化/生理作用
IgG促进细胞介导的抗体依赖性细胞毒性（ADCC）。它还有助于激活补体系统的经典途径。IgG 中和病毒颗粒和毒素。IgM是在免疫应答早期表达的抗体，它有助于吞噬凋亡细胞。它具有多反应和自动反应功能。IgM通过介导组织基分子的清除，诱导组织稳态。较低的血清IgM水平与增强的自身免疫反应和较高的感染风险有关。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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