biological source
goat
Quality Level
conjugate
peroxidase conjugate
antibody form
F(ab′)2 fragment of affinity isolated antibody
antibody product type
secondary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
concentration
0.8 mg/mL
technique(s)
ELISA: suitable, western blot: suitable
shipped in
wet ice
target post-translational modification
unmodified
General description
免疫球蛋白G（IgG）是人血清中最丰富的免疫球蛋白。IgM 占到了总血清免疫球蛋白的5-10%。这些免疫球蛋白包含四条多肽链，包括两条重链（H）和两条轻链（L）。这些多肽链通过二硫键相互连接。IgM是脊椎动物中高度保守的抗体。IgM以五聚体的形式存在。IgG和IgM都由B细胞分泌。
Application
山羊抗小鼠IgG& IgM抗体（HRP偶联物）已用于蛋白质印迹（1：400）和免疫荧光（1：500）。
Biochem/physiol Actions
IgG促进细胞介导的抗体依赖性细胞毒性（ADCC）。它还有助于激活补体系统的经典途径。IgG 中和病毒颗粒和毒素。IgM是在免疫应答早期表达的抗体，它有助于吞噬凋亡细胞。它具有多反应和自动反应功能。IgM通过介导组织基分子的清除，诱导组织稳态。较低的血清IgM水平与增强的自身免疫反应和较高的感染风险有关。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Chapter 12 - Immunoglobulin Titers and Immunoglobulin Subtypes
Gleason CA and Devaskar SU
Acanthamoeba: Biology and Pathogenesis (2011)
Caroline Grönwall et al.
Frontiers in immunology, 3, 66-66 (2012-05-09)
Antibodies are a vital part of the armamentarium of the adaptive immune system for the fine-tuning of the recognition and response to foreign threats. However, in health there are some types of antibodies that instead recognize self-antigens and these contribute
Dusan Bencina et al.
Avian pathology : journal of the W.V.P.A, 34(6), 463-472 (2006-03-16)
Maternal antibodies can protect avian embryos against vertically transmitted pathogens during embryogenesis and also young birds after hatching. In contrast to the well-known transfer of maternal immunoglobulin (Ig) G (also termed IgY) from the yolk to embryonic blood, information about
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| AP130P | 04053252469497 |