推荐产品
生物来源
rabbit
质量水平
偶联物
peroxidase conjugate
抗体形式
F(ab′)2 fragment of affinity isolated antibody
抗体产品类型
secondary antibodies
克隆
polyclonal
种属反应性
mouse
制造商/商品名称
Chemicon®
技术
ELISA: suitable
western blot: suitable
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
免疫球蛋白G(IgG) 是在人类血清中发现的最丰富的糖蛋白抗体。它是由B细胞分泌的。IgG结构包含4条多肽链,其中包括两条相同的重(H)链和两条完全相同的λ轻(L)链。这些链通过二硫键相互连接。IgG以IgG1、IgG2、IgG3和IgG4四种亚型存在。
应用
兔抗小鼠IgG抗体,HRP偶联物已用于蛋白质印迹。(1:2000)(1:200000)(1:5000)
生化/生理作用
免疫球蛋白G(IgG)有助于补体系统的激活。它中和病毒颗粒和毒素。IgG促进抗体依赖性细胞介导的细胞毒性(ADCC)。母体IgG通过胎盘转移到 胎儿 ,这对于保护新生儿免受 传染病的侵害至关重要。检测严重急性呼吸系统综合征冠状病毒(SARS-CoV)2型感染患者的IgG水平可能是评估2019冠状病毒病(COVID-19)严重程度和预后的一种潜在策略。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
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储存分类代码
13 - Non Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 23(12), 4276-4287 (2009-08-29)
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Neuron-glia communication: metallothionein expression is specifically up-regulated by astrocytes in response to neuronal injury.
Journal of Neurochemistry null
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