一般描述
免疫球蛋白G（IgG） 是在人类血清中发现的最丰富的糖蛋白抗体。它是由B细胞分泌的。IgG结构包含4条多肽链，其中包括两条相同的重（H）链和两条完全相同的λ轻（L）链。这些链通过二硫键相互连接。IgG以IgG1、IgG2、IgG3和IgG4四种亚型存在。
应用
兔抗小鼠IgG抗体，HRP偶联物已用于蛋白质印迹。(1:2000)(1:200000)(1:5000)
生化/生理作用
免疫球蛋白G（IgG）有助于补体系统的激活。它中和病毒颗粒和毒素。IgG促进抗体依赖性细胞介导的细胞毒性（ADCC）。母体IgG通过胎盘转移到 胎儿 ，这对于保护新生儿免受 传染病的侵害至关重要。检测严重急性呼吸系统综合征冠状病毒（SARS-CoV）2型感染患者的IgG水平可能是评估2019冠状病毒病（COVID-19）严重程度和预后的一种潜在策略。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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