一般描述
免疫球蛋白G（IgG）是人血清中最常见的抗体类型。IgG以IgG1、IgG2、IgG3和IgG4四种亚型存在。IgG 由B细胞产生。IgG结构具有四条多肽链，包括两条相同的重链（H）和两条相同的或λ轻链（L）。这些链通过二硫键相互连接。
应用
HRP 标记山羊抗豚鼠IgG抗体可用于免疫印迹分析和酶联免疫吸附测定(ELISA)（1:2000）。
生化/生理作用
免疫球蛋白G（IgG）启动补体系统的经典途径。它中和病毒颗粒和毒素。IgG在抗体依赖性细胞介导的细胞毒性（ADCC）中起着至关重要的作用。母体IgG通过胎盘转移到 胎儿 ，这对于保护新生儿免受 传染病的侵害至关重要。严重急性呼吸综合征冠状病毒（SARS-CoV）-2感染患者的IgG水平可作为评估2019冠状病毒疾病（COVID-19）严重程度和预后的潜在工具。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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