产品名称
抗-小鼠IgM(-链特异性)−琼脂糖 山羊抗, IgG fraction of antiserum, saline suspension
biological source
goat
conjugate
agarose conjugate
antibody form
IgG fraction of antiserum
antibody product type
secondary antibodies
clone
polyclonal
form
saline suspension
species reactivity
mouse
extent of labeling
≥5 mg per mL
technique(s)
Ouchterlony double diffusion: suitable
capacity
0.4 mg binding capacity
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Application
成功使用该抗体的应用以及相关的同行评审论文如下所示。
染色质免疫沉淀分析(1篇论文)
染色质免疫沉淀分析(1篇论文)
为了分离与 IgM 重链融合的嵌合蛋白,将CHO 上清液在装有琼脂糖连接的山羊抗小鼠 IgM mu 链特异性色谱柱上进行电泳。
山羊抗小鼠 IgM(μ-链特异性)琼脂糖抗体可用于原代脾细胞的琼脂糖结合测定,以及可溶性晶状体蛋白和骨髓性白血病细胞系的免疫沉淀。
山羊抗小鼠IgM(μ-链特异性)琼脂糖抗体可用于免疫沉淀反应和ChIP测定。该产品也可用于Ouchterlony双扩散应用。
Biochem/physiol Actions
IgM显示出多反应和自动反应功能。它可通过介导基于组织的分子的清除在组织动态平衡中起关键作用。IgM具有与N-连接的糖基化位点,其中糖分别为甘露糖、半乳糖、N-乙酰氨基葡萄糖和唾液酸。IgM在吞噬凋亡细胞中发挥关键作用。血清IgM水平降低会导致自身免疫反应增强,并增加感染风险。IgM连接的琼脂糖树脂经检测是有效的结合物结合。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
IgM 是一种调节体液免疫反应的糖蛋白抗体。小鼠IgM参与调节B细胞记忆。该抗体同种型还涉及与小鼠1型糖尿病发病机理相关的自身免疫反应的发展。
当针对纯化的小鼠IgA、IgG(所有亚类)和IgM骨髓瘤蛋白进行测试时,山羊抗小鼠IgM(μ-链特异性)-琼脂糖抗体对小鼠IgM具有特异性。
当针对纯化的小鼠IgA、IgG(所有亚类)和IgM骨髓瘤蛋白进行测试时,山羊抗小鼠IgM(μ-链特异性)-琼脂糖抗体对小鼠IgM具有特异性。
IgM以五聚体形式存在,由腹膜B细胞分泌。IgM是一种脊椎动物中高度保守的抗体,在免疫应答过程中早期表达。
Physical form
悬浮于含保存剂的0.5 M NaCl中。
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存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
常规特殊物品
此项目有
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