biological source
mouse
Quality Segment
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
1F5, monoclonal
form
buffered aqueous solution
species reactivity
human
technique(s)
indirect ELISA: suitable, western blot: 1-5 μg/mL
isotype
IgG1κ
GenBank accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... TRPV1(7442)
General description
基因编码瞬时受体电位阳离子通道,亚族V,成员1(TRPV1)定位到人类染色体17p13。它是非选择性阳离子通道。该蛋白在气道神经纤维上表达。它也在感觉神经元中强烈表达。
Immunogen
TRPV1(NP_542437, 21 a.a.~ 124 a.a)带有GST标签的部分重组蛋白。仅GST标签的MW为26 KDa。
序列
CPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQ
序列
CPDPLDGDPNSRPPPAKPQLSTAKSRTRLFGKGDSEEAFPVDCPHEEGELDSCPTITVSPVITIQRPGDGPTGARLLSQDSVAASTEKTLRLYDRRSIFEAVAQ
Biochem/physiol Actions
瞬时受体电位阳离子通道亚家族V成员1(TRPV1)是辣椒素受体。它参与疼痛感知。TRPV1还调节传入信号和支气管收缩。在大脑中,它调节神经元功能、运动行为和神经炎症。辣椒素在TRPV1的激活中起着重要作用。
Physical form
溶于pH7.4的磷酸盐缓冲盐水中的溶液
Legal Information
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Disclaimer
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存储类别
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)