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900862

Sigma-Aldrich

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

别名:

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

经验公式（希尔记法）:
C14H15F3N2OSi
CAS号:
2187374-13-4
分子量:
312.36
UNSPSC代码:
12352200
NACRES:
NA.22

方案

≥95%

表单

powder or crystals

储存温度

−20°C

SMILES字符串

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

应用

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

其他说明

Technology Spotlight: Trifunctional Probe Building Blocks

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储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

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分析证书(COA)

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Trifunctional Probe Building Blocks

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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