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Merck
CN

900615

Sigma-Aldrich

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone

≥95%

别名:

Hydroxyl benzophenone alkyne, Probe building block

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About This Item

经验公式(希尔记法):
C16H12O3
分子量:
252.26
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.22

质量水平

方案

≥95%

表单

solid

反应适用性

reaction type: click chemistry

储存温度

−20°C

SMILES字符串

O(CC#C)c1ccc(cc1)C(=O)c2ccc(cc2)O

InChI

1S/C16H12O3/c1-2-11-19-15-9-5-13(6-10-15)16(18)12-3-7-14(17)8-4-12/h1,3-10,17H,11H2

InChI key

TZKIHDJSIXVMIQ-UHFFFAOYSA-N

应用

(4-Hydroxyphenyl)(4-(prop-2-yn-1-yloxy)phenyl)methanone is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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说明
价格

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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商品

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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