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Merck
CN

900613

Sigma-Aldrich

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid

≥95%

别名:

Carboxyl benzophenone alkyne, Probe building block

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About This Item

经验公式(希尔记法):
C21H20O5
分子量:
352.38
MDL编号:
UNSPSC代码:
12352106
NACRES:
NA.22

质量水平

方案

≥95%

表单

solid

反应适用性

reaction type: click chemistry

储存温度

−20°C

SMILES字符串

O(CCCCC(=O)O)c1ccc(cc1)C(=O)c2ccc(cc2)OCC#C

InChI

1S/C21H20O5/c1-2-14-25-18-10-6-16(7-11-18)21(24)17-8-12-19(13-9-17)26-15-4-3-5-20(22)23/h1,6-13H,3-5,14-15H2,(H,22,23)

InChI key

PVDBYWSDYKTIBJ-UHFFFAOYSA-N

应用

5-(4-(4-(Prop-2-yn-1-yloxy)benzoyl)phenoxy)pentanoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

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In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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