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Merck
CN

900865

Sigma-Aldrich

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

别名:

Formyl sulfonyl fluoride TMS-Alkyne, Probe building block

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About This Item

经验公式(希尔记法):
C12H13FO3SSi
分子量:
284.38
UNSPSC代码:
12352200
NACRES:
NA.22

方案

≥95%

表单

powder or crystals

反应适用性

reaction type: click chemistry

储存温度

−20°C

SMILES字符串

O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1

应用

4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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说明
价格

储存分类代码

10 - Combustible liquids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

新产品

从最新的版本中选择一种:

分析证书(COA)

Lot/Batch Number

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商品

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

在与K. Barry Sharpless及其同事合作后,Sigma-Aldrich现可提供各种磺酰氟试剂,这些试剂经历了“Click II”反应。

In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

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