900865
4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride
≥95%
别名:
Formyl sulfonyl fluoride TMS-Alkyne, Probe building block
产品名称
4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride, ≥95%
SMILES string
O=CC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1
assay
≥95%
form
powder or crystals
reaction suitability
reaction type: click chemistry
storage temp.
−20°C
Application
4-Formyl-2-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
存储类别
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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商品
In collaboration with K. Barry Sharpless and coworkers, we offer a variety of sulfonyl fluoride reagents that undergo a “Click II” reaction.
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
在与K. Barry Sharpless及其同事合作后，Sigma-Aldrich现可提供各种磺酰氟试剂，这些试剂经历了“Click II”反应。
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
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