质量水平
检测方案
≥95%
形式
solid
反应适用性
reaction type: click chemistry
reagent type: cross-linking reagent
官能团
alkyne
carboxylic acid
储存温度
−20°C
SMILES字符串
O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2
InChI
1S/C17H12O4/c1-2-11-21-15-9-7-13(8-10-15)16(18)12-3-5-14(6-4-12)17(19)20/h1,3-10H,11H2,(H,19,20)
InChI key
URDMKFAPEKSQDV-UHFFFAOYSA-N
应用
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他说明
Technology Spotlight: Trifuctional Probe Building Blocks
A library approach to rapidly discover photoaffinity probes of the mRNA decapping scavenger enzyme DcpS
Synthesis and Evaluation of New Thiodigalactoside-Based Chemical Probes to Label Galectin-3
Discovery of tumor-specific irreversible inhibitors of stearoyl CoA desaturase
相关产品
产品编号
说明
价格
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
商品
In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.
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