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SIRNA

MISSION® siRNA产品系列

Custom and Predesigned siRNA

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别名:
siRNA, siRNA混合库, 定制siRNA, 预设计siRNA, 高通量siRNA
UNSPSC代码:
12352208
Antonis C Antoniou et al.
The New England journal of medicine, 371(6), 497-506 (2014-08-08)
Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown. We analyzed the risk of breast cancer among 362 members of
Fuhui Xu et al.
PloS one, 9(9), e106509-e106509 (2014-09-04)
Improved drought tolerance is always a highly desired trait for agricultural plants. Significantly increased drought tolerance in Arabidopsis thaliana (Columbia-0) has been achieved in our work through the suppression of ESKMO1 (ESK1) gene expression with small-interfering RNA (siRNA) and overexpression
Chong He et al.
PLoS genetics, 10(12), e1004860-e1004860 (2014-12-19)
The common non-steroidal anti-inflammatory drug ibuprofen has been associated with a reduced risk of some age-related pathologies. However, a general pro-longevity role for ibuprofen and its mechanistic basis remains unclear. Here we show that ibuprofen increased the lifespan of Saccharomyces
Maria Dermit et al.
Developmental cell, 55(3), 298-313 (2020-11-11)
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a
Jieru E Lin et al.
Cancer research, 76(2), 339-346 (2016-01-17)
Obesity is a well-known risk factor for colorectal cancer but precisely how it influences risks of malignancy remains unclear. During colon cancer development in humans or animals, attenuation of the colonic cell surface receptor guanylyl cyclase C (GUCY2C) that occurs

商品

If you commercialize Molecular Diagnostics (MDx), develop Laboratory Developed Tests (LDTs), or conduct preclinical research on therapeutics, then your final kit, assay, or modality must have an extraordinary level of quality to comply with strict regulatory or study standards.

我们为预设计siRNA及siRNA文库提供了先进的设计与高品质合成,利用Rosetta siRNA设计算法以降低脱靶效应并提高RNAi的效果。此算法利用位点特异性打分矩阵(PSSM)及非常重要的siRNA种子区域知识,预测目标靶基因最具效率和特异性的siRNA序列。

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Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

WellRED oligos use cyanine-based fluorescent dyes with high extinction coefficients that absorb in the near-infrared region, thereby reducing background noise from biological materials, resulting in highly sensitive detection.

We can quickly synthesize and ship custom siRNA using your sequences.

如果您计划进行分子诊断(MDx)商业化,开发实验室开发试验(LDT),或进行治疗学临床前研究,最终的成品试剂盒、检测试剂或药品必须具有非凡的质量水平,符合严苛的监管或研究标准。

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