跳转至内容

尊敬的客户：

目前国际形势复杂多变，关税政策尚不明朗，这可能对我们的产品价格产生一定影响。在此情况下，我们希望就订单事宜与您进行友好沟通。

基于当前的不确定性，如果您选择在此期间下单，我们将保留根据实际情况调整价格的权利。同时，我们也理解市场变化可能给您带来的困扰，因此如果在订单实际发货前因关税政策变动导致价格出现较大波动，默克将与您进行协商讨论并视情况对订单进行调整或取消。

Merck
CN
所有图片(4)

主要文件

查看所有文档

B9285

Sigma-Aldrich

5-溴-2′-脱氧尿苷

BioUltra, ≥99%

别名:

5-BrdU, 5-溴-1-(2-脱氧-β-D-呋喃核糖)尿嘧啶, 5-溴脱氧尿苷, BUdR

登录查看公司和协议定价

选择尺寸

50 MG
¥742.44
250 MG
¥1,298.61
1 G
¥3,898.56

¥742.44

国内现货，预计发货时间2025年4月24日详情

所有图片(4)

选择尺寸

变更视图
50 MG
¥742.44
250 MG
¥1,298.61
1 G
¥3,898.56

About This Item

经验公式（希尔记法）:
C9H11BrN2O5
CAS号:
59-14-3
分子量:
307.10
Beilstein:
30395
EC 号:
200-415-9
MDL编号:
MFCD00006529
UNSPSC代码:
41106305
PubChem化学物质编号:
24892132
NACRES:
NA.51

¥742.44

国内现货，预计发货时间2025年4月24日详情

生物来源

synthetic (organic)

质量水平

200

产品线

BioUltra

方案

≥99%

表单

powder

杂质

≤0.005% Phosphorus (P)
≤0.1% Insoluble matter

灼烧残渣

≤0.1%

mp

191-194 °C (dec.) (lit.)

溶解性

NH4OH: 0.1 M at 20 °C, clear, colorless

痕量阳离子

Al: ≤0.0005%
Ca: ≤0.01%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

正在寻找类似产品? 访问 产品对比指南

相关类别

比较类似商品

查看完整比较结果

显示差异

1 of 4

此商品
B5002B0631I7125
5-溴-2′-脱氧尿苷 BioUltra, ≥99%

B9285

5-溴-2′-脱氧尿苷

5-溴-2′-脱氧尿苷 ≥99% (HPLC)

B5002

5-溴-2′-脱氧尿苷

5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt ≥90%

B0631

5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt

5-碘-2′-脱氧尿苷 ≥99% (HPLC)

I7125

5-碘-2′-脱氧尿苷

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

assay

≥99%

assay

≥99% (HPLC)

assay

≥90%

assay

≥99% (HPLC)

form

powder

form

powder

form

powder

form

powder or crystals

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

NH4OH: 0.1 M at 20 °C, clear, colorless

solubility

DMSO: 50 mg/mL, clear, colorless to very faintly yellow

solubility

water: 50 mg/mL, clear, colorless to faintly yellow

solubility

1 N NH4OH: 50 mg/mL, clear to very slightly hazy, colorless to light yellow

一般描述

5′-溴-2-脱氧尿苷(BrdU)是一种可被皮肤吸收或吸入的致癌物质。BrdU溶液对光敏感。[1]

应用

5-溴-2′-脱氧尿苷已用于：
  • 在细胞增殖测定中标记妊娠小鼠的增殖细胞[2]
  • 研究缺血后不同时间的细胞增殖时程[3]确认MKI67 +细胞在细胞周期中重新进入生殖细胞[4]
  • 成纤维细胞5′-溴-2′脱氧尿苷(BrdUrd)染色[5]

生化/生理作用

5′-溴-2-脱氧尿苷(BrdU)染色主要用于体内观察肿瘤细胞和其他组织的增殖。[6]
5-溴-2′-脱氧尿苷（5-BrdU）是一种胸苷类似物，可掺入DNA中。 5-BrdU通常广泛用于测定DNA合成和标记分裂细胞。 因此，5-BrdU常用于研究细胞信号传导和诱导细胞增殖的其他过程。
用作遗传研究中诱变剂的胸苷类似物。在 S 期可选择性结合到细胞 DNA 中。

其他说明

2024年CiteAb奖——成功的帕金森研究供应商(2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research)

象形图

Health hazard
GHS08

警示用语：

Danger

危险声明

H340,H361fd

危险分类

Muta. 1B - Repr. 2

储存分类代码

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

个人防护装备

Eyeshields, Gloves, type N95 (US)

  • 技术规格说明书

    • 历史批次信息供参考:

    分析证书(COA)

    Lot/Batch Number
    HMBK5068
    HMBK2172
    HMBJ9646
    HMBJ5521
    HMBJ1524

    没有发现合适的版本？

    如果您需要特殊版本，可通过批号或批次号查找具体证书。

    搜索COA

    已有该产品？

    在文件库中查找您最近购买产品的文档。

    访问文档库

    1. Which document(s) contains shelf-life or expiration date information for a given product?

      If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

    2. How do I get lot-specific information or a Certificate of Analysis?

      The lot specific COA document can be found by entering the lot number above under the "Documents" section.

    3. How do I find price and availability?

      There are several ways to find pricing and availability for our products. Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers.

    4. What is the Department of Transportation shipping information for this product?

      Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

    5. Can Product B9285, 5-Bromo-2´-deoxyuridine, be injected into animals?

      Sigma has not injected animals with solutions of this compound, so we do not have a stepwise procedure for you.  However, this application has been reported in the literature.  Please see the cited references below, which you may find useful. Several references cite the use of Product No. B9285 in their protocols.1. Yin, X-X, et al., Expression of active caspase-3 in mitotic and postmitotic cells of the rat forebrain. J. Comp. Neurol., 433(1), 4-22 (2001).  Injected into mice at 50 mg/kg.2. Dackor, R.T., et al., Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene. Mol. Cell. Biol., 26(7), 2511-2518 (2006).  Injected into mice at 100 mg/kg.3. Farris, S.M., et al., Larval and Pupal Development of the Mushroom Bodies in the Honey Bee, Apis mellifera. J. Comp. Neurol., 414, 97-113 (1999).  A 25 mg/mL solution was injected into bee larvae, prepupae, and pupae.4. Gaiano, N., et al., Radial Glial Identity Is Promoted by Notch1 Signaling in the Murine Forebrain. Neuron, 26(2), 395-404 (2000).  A 20 mg/mL solution was injected into mice.

    6. For how long is Product B9285, 5-Bromo-2´-deoxyuridine, stable in solution?

      5-Bromo-2´-deoxyuridine is stable in solution for 6 months when stored -20°C.

    7. In what solvents is Product B9285, 5-Bromo-2´-deoxyuridine, soluble?

      Solubility information for 5-bromo-2´-deoxyuridine can be found on the product information sheet (under Documents, above).

    8. What is the shelf life of Product No. B9285 (5-bromo-2´-deoxyuridine)?

      Sigma-Aldrich does not assign an expiration date to this product; it is guaranteed for one year from the date of shipment.

    9. My question is not addressed here, how can I contact Technical Service for assistance?

      Ask a Scientist here.

    Retinoic Acid Induces Multiple Hallmarks of the Prospermatogonia-to-Spermatogonia Transition in the Neonatal Mouse
    Busada JT, et al.
    Biology of Reproduction, 90(3) (2014)
    Histological, cellular and behavioral assessments of stroke outcomes after photothrombosis-induced ischemia in adult mice
    Li H, et al.
    BMC Neuroscience, 15(1), 1-13 (2014)
    Identification of MYC-Dependent Transcriptional Programs in Oncogene-Addicted Liver Tumors
    Kress TR, et al.
    Cancer research, 76(12), 3463-3472 (2016)
    Hydrops Fetalis, Cardiovascular Defects, and Embryonic Lethality in Mice Lacking the Calcitonin Receptor-Like Receptor Gene
    Dackor RT, et al.
    Molecular and Cellular Biology, 26(7), 2511-2518 (2006)
    Non-canonical Cyclic Nucleotides (2017)
    查看所有相关文献

    我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

    联系客户支持