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主要文件

安全信息

A8556

Sigma-Aldrich

6′-唾液酸乳糖 钠盐

from bovine milk or colostrum, ≥97% (HPLC)

别名:

α-NeuNAc-(2→6)-β-D-Gal-(1→4)-D-Glc, 6′-N-乙酰神经氨酸-乳糖 钠盐, 6′-SL

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1 G
¥3,832.67
5 G
¥14,190.36

¥3,832.67


国内现货,预计发货时间2025年4月25日详情


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选择尺寸

变更视图
1 G
¥3,832.67
5 G
¥14,190.36

About This Item

线性分子式:
C23H38NO19Na
分子量:
655.53
UNSPSC代码:
12352201
NACRES:
NA.25

¥3,832.67


国内现货,预计发货时间2025年4月25日详情


获取大包装报价

生物来源

bovine milk or colostrum

质量水平

方案

≥97% (HPLC)

表单

powder

杂质

≤1% free N-Acetyl Neuraminic Acid
≤11% water (Karl Fischer)

颜色

white to off-white

溶解性

water: 20 mg/mL, clear, colorless

痕量阳离子

Na: 2.6-4.5% (anhydrous)

储存温度

−20°C

SMILES字符串

[Na+].[H][C@]1(O[C@](C[C@H](O)[C@H]1NC(C)=O)(OC[C@H]2OC(O)[C@H](O)[C@@H](O)[C@@H]2O[C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)C([O-])=O)[C@H](O)[C@H](O)CO

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174091740817245
technique(s)

immunoprecipitation (IP): suitable

technique(s)

immunoprecipitation (IP): suitable

technique(s)

immunoprecipitation (IP): suitable

technique(s)

immunoprecipitation (IP): suitable

manufacturer/tradename

EZ-ChIP

manufacturer/tradename

Magna ChIP®

manufacturer/tradename

Magna ChIP®

manufacturer/tradename

Upstate®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

shipped in

wet ice

shipped in

dry ice

shipped in

dry ice

shipped in

-

应用

6'-唾液酸乳糖是一种化合物,其中乙酰神经氨酸 (NANA) 单元在 6 位与乳糖的半乳糖基单元连接。在 3'-唾液酸乳糖中,该连接位于 3 位。3'-唾液酸乳糖和 6′-唾液酸乳糖用于区分和表征病毒的结合域,如流感病毒和鼻炎病毒,它们识别 NANA 封端细胞表面受体。3'-唾液酸乳糖和 6'-唾液酸乳糖用作分析方法中的引用化合物,用于测定乳汁和初乳等物质中是否存在唾液酸乳糖。

其他说明

为了全面了解我们针对客户研究提供的各种寡糖产品,建议您访问我们的碳水化合物分类页面。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

法规信息

监管及禁止进口产品
  • 技术规格说明书

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    Maria Elena Ortiz-Soto et al.
    PloS one, 11(5), e0155410-e0155410 (2016-05-12)
    Sialyltransferases (STs) are disulfide-containing, type II transmembrane glycoproteins that catalyze the transfer of sialic acid to proteins and lipids and participate in the synthesis of the core structure oligosaccharides of human milk. Sialic acids are found at the outermost position
    Ousman Jobe et al.
    Journal of leukocyte biology, 99(6), 1089-1106 (2015-12-17)
    Monocytes and monocyte-derived macrophages express relatively low levels of CD4. Despite this, macrophages can be effectively infected with human immunodeficiency virus type 1. Macrophages have a critical role in human immunodeficiency virus type 1 transmission; however, the mechanism or mechanisms
    Rit Bahadur Gurung et al.
    Regulatory toxicology and pharmacology : RTP, 95, 182-189 (2018-03-21)
    We performed a series of toxicity studies on the safety of 6'-sialyllactose (6'-SL) sodium salt as a food ingredient. 6'-SL sodium salt, up to a maximum dose of 5000 μg/plate, did not increase the number of revertant colonies in five
    Shuang-Xi Chen et al.
    Neural regeneration research, 15(6), 1058-1065 (2019-12-12)
    Oxidative stress contributes to the pathogenesis of neurodegenerative diseases. With the aim to find reagents that reduce oxidative stress, a phage display library was screened for peptides mimicking α2,6-sialyllactose (6'-SL), which is known to beneficially influence neural functions. Using Sambucus
    Yongkun Chen et al.
    Science China. Life sciences, 61(7), 836-843 (2018-02-16)
    Human influenza viruses preferentially bind to sialic acid-α2,6-galactose (SAα2,6Gal) receptors, which are predominant in human upper respiratory epithelia, whereas avian influenza viruses preferentially bind to SAα2,3Gal receptors. However, variants with amino acid substitutions around the receptor-binding sites of the hemagglutinin

    商品

    O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

    O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上,并可占总量的50-80%。

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