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Merck
CN

A6936

Sigma-Aldrich

3′-N-乙酰神经氨酸-N-乙酰基乳糖胺 钠盐

≥95%

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别名:
α-NeuNAc-(2→3)-β-D-Gal-(1→4)-D-GlcNAc, 3′-SLN, 3′-唾液酰-N-乙酰乳糖胺
经验公式(希尔记法):
C25H42N2O19 · xNa+
CAS号:
分子量:
674.60 (free acid basis)
MDL编号:
UNSPSC代码:
12352201
PubChem化学物质编号:
NACRES:
NA.25

质量水平

检测方案

≥95%

形式

solid

储存温度

−20°C

SMILES字符串

CC(=O)NC(C=O)C(O)C(OC1OC(CO)C(O)C(OC2(CC(O)C(NC(C)=O)C(O2)C(O)C(O)CO)C(O)=O)C1O)C(O)CO

InChI

1S/C25H42N2O19/c1-8(32)26-10(4-28)16(37)20(13(36)6-30)44-23-19(40)22(18(39)14(7-31)43-23)46-25(24(41)42)3-11(34)15(27-9(2)33)21(45-25)17(38)12(35)5-29/h4,10-23,29-31,34-40H,3,5-7H2,1-2H3,(H,26,32)(H,27,33)(H,41,42)

InChI key

RGZDLTASXRMKKF-UHFFFAOYSA-N

应用

3′-N-乙酰神经氨酰-N-乙酰乳糖胺是O-糖肽中的糖基组分。3′-唾液酰-N-乙酰乳糖胺可用于制备禽类受体类似物糖基探针,用于研究流感病毒的结合性,如北美H7N2亚型病毒A/New York/107/2003 (NY107)。3′-唾液酰-N-乙酰乳糖胺可作为牛奶寡糖分析的参考标准品。

其他说明

为了全面了解我们针对客户研究提供的各种多糖产品,建议您访问我们的碳水化合物分类页面。

象形图

Skull and crossbones

警示用语:

Danger

危险声明

预防措施声明

危险分类

Acute Tox. 1 Oral

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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A S Edge et al.
The Journal of biological chemistry, 262(33), 16135-16141 (1987-11-25)
Examination by gel filtration, thin layer and anion exchange chromatography of the O-linked carbohydrate units released from fetuin by alkaline borohydride treatment indicated the presence in this glycoprotein of an acidic glucosamine-containing hexasaccharide in addition to the previously described tetra-
Maria Lorna A De Leoz et al.
Journal of the American Society for Mass Spectrometry, 30(3), 426-438 (2018-12-20)
Reference spectral library searching, while widely used to identify compounds in other areas of mass spectrometry, is not commonly used in glycomics. Building on a study by Cotter and coworkers on analysis of sialylated oligosaccharides using atmospheric pressure-matrix-assisted laser-induced tandem
Melanie Koehler et al.
Nature communications, 10(1), 4460-4460 (2019-10-03)
Viral infection is an intricate process that requires the concerted action of both viral and host cell components. Entry of viruses into cells is initiated by interactions between viral proteins and their cell surface receptors. Despite recent progress, the molecular

商品

O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上,并可占总量的50-80%。

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