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Merck
CN

A8681

3′-唾液酸乳糖

from bovine milk or colostrum, ≥97% (HPLC)

别名:

α-NeuNAc-(2→3)-β-D-Gal-(1→4)-D-Glc, 3′-SL, 3′-唾液酸-D-乳糖, 3&8242-N-乙酰神经氨酸乙酯-D-乳糖 钠盐, NANA-乳糖

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关于此项目

经验公式（希尔记法）:
C23H39NO19
化学文摘社编号:
35890-38-1
分子量:
633.55
UNSPSC Code:
12352201
NACRES:
NA.25
PubChem Substance ID:
24891358
MDL number:
MFCD00166999
Beilstein/REAXYS Number:
75357

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产品名称

3′-唾液酸乳糖, from bovine milk or colostrum, ≥97% (HPLC)

InChI

1S/C23H39NO19.Na/c1-7(29)24-13-8(30)2-23(22(38)39,42-19(13)15(35)10(32)4-26)43-20-16(36)12(6-28)40-21(17(20)37)41-18(11(33)5-27)14(34)9(31)3-25;/h3,8-21,26-28,30-37H,2,4-6H2,1H3,(H,24,29)(H,38,39);/q;+1/p-1/t8-,9-,10+,11+,12+,13+,14+,15+,16-,17+,18+,19+,20-,21-,23-;/m0./s1

SMILES string

[Na+].[H]C(=O)[C@H](O)[C@@H](O)[C@H](O[C@@H]1O[C@H](CO)[C@H](O)[C@H](O[C@@]2(C[C@H](O)[C@@H](NC(C)=O)[C@@H](O2)[C@H](O)[C@H](O)CO)C([O-])=O)[C@H]1O)[C@H](O)CO

InChI key

LTWFUJWFLMHANB-TZCPRLTCSA-M

biological source

bovine milk or colostrum

assay

≥97% (HPLC)

form

powder

color

white

solubility

water: 20 mg/mL, clear, colorless

cation traces

Na: 3.1-4.7%

storage temp.

−20°C

Quality Level

200

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相关类别

Application

3′-唾液乳糖是一种化合物，在乙酰神经氨酰（NANA）单元中，在 3 号位连接乳糖的半乳糖单元。在 6′-唾液乳糖中，在 6 号位产生这种连接。3′-唾液酸乳糖和 6′-唾液酸乳糖用于区分和表征病毒（如流感病毒和鼻炎病毒）的结合域，它们能识别 NANA 覆盖的细胞表面受体。3′-唾液乳糖和 6′-唾液乳糖用作测量其在牛奶和初乳等材料中的含量的分析方法中的参考化合物。

Other Notes

为了全面了解我们针对客户研究提供的各种寡糖产品，建议您访问我们的碳水化合物分类页面。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLBZ2298
SLBX4359
SLBV2319
SLBT8124
SLBM8426V

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Tadasu Urashima et al.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 146(2), 153-159 (2006-11-23)
Samples of milk from a Bryde's whale and a Sei whale contained 2.7 g/100 mL and 1.7 g/100 mL of hexose, respectively. Both contained lactose as the dominant saccharide along with small amounts of Neu5Ac(alpha2-3)Gal(beta1-4)Glc (3'-N-acetylneuraminyllactose), Neu5Ac(alpha2-6)Gal(beta1-4)Glc (6'-N-acetylneuraminyllactose) and Neu5Ac(alpha2-6)Gal(beta1-4)GlcNAc(beta1-3)Gal(beta1-4)Glc
T Nakamura et al.
Carbohydrate research, 329(2), 471-476 (2000-12-16)
The composition of the products formed by treatment of commercial alpha-Neu5Ac-(2 --> 3)-beta-D-Galp-(1 --> 4)-D-Glc (3'-sialyllactose) with glacial acetic acid was investigated by 1H-13C one- and two-dimensional NMR spectroscopy and fast atom bombardment-mass spectrometry. The data confirmed that the major
A Zintl et al.
Parasitology, 125(Pt 1), 45-50 (2002-08-09)
The process of host cell invasion by Babesia divergens is poorly understood and improved knowledge of the mechanism involved could lead to development of measures effective in disease prevention. The investigate parasite ligands on the erythrocyte surface, B. divergens cultures
Oriane Machon et al.
Glycobiology, 27(2), 123-128 (2016-11-01)
Glycosylation is a group of post-translational modifications that displays a large variety of structures and are implicated in a plethora of biological processes. Therefore, studying glycosylation requires different technical approaches and reliable tools, lectins being part of them. Here, we
S Crennell et al.
Nature structural biology, 7(11), 1068-1074 (2000-11-04)
Paramyxoviruses are the main cause of respiratory disease in children. One of two viral surface glycoproteins, the hemagglutinin-neuraminidase (HN), has several functions in addition to being the major surface antigen that induces neutralizing antibodies. Here we present the crystal structures
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O-Linked glycoproteins are usually large proteins with a molecular mass of >200 kDa. Glycosylation generally occurs in high-density clusters and may represent as much as 50-80% of the overall mass.

O-连接糖蛋白回顾

O-连接糖蛋白通常是分子量>200kDa的大蛋白。糖基化通常发生在高密度簇上，并可占总量的50-80%。

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