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安全和法规

L0750500

Lorazepam

Name: Lorazepam
Brand: SIAL

European Pharmacopoeia (EP) Reference Standard

别名:

(±)-Lorazepam, 7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one

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About This Item

经验公式（希尔记法）:

C₁₅H₁₀Cl₂N₂O₂

CAS号:

846-49-1

分子量:

321.16

MDL编号:

MFCD00063406

UNSPSC代码:

41116107

PubChem化学物质编号:

329817375

NACRES:

NA.24

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USP

1370305

Lorazepam

Sigma-Aldrich

A8800

阿普唑仑

BP434

劳拉西泮标准液

Sigma-Aldrich

D0899

地西泮

Sigma-Aldrich

C1277

氯硝西泮

Sigma-Aldrich

L1764

(±)-Lorazepam

USP

1185008

地西泮

D0940000

地西泮

A0357000

阿普唑仑

USP

1370338

2-氨基-2′,5-二氯苯甲酮

等级

pharmaceutical primary standard

API类

lorazepam

制造商/商品名称

EDQM

药品控制

regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

应用

pharmaceutical (small molecule)

包装形式

neat

SMILES字符串

OC1N=C(c2ccccc2Cl)c3cc(Cl)ccc3NC1=O

InChI

1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)

InChI key

DIWRORZWFLOCLC-UHFFFAOYSA-N

基因信息

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

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一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Lorazepam EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

包装

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

1370327

1370349

1370350

1370360

BP434

劳拉西泮标准液, British Pharmacopoeia (BP) Reference Standard

BP376

6-氯-4-(2-氯苯基)喹唑啉-2-甲醛, British Pharmacopoeia (BP) Reference Standard

象形图

GHS08

警示用语：

Warning

危险声明

H361d

预防措施声明

P201 - P202 - P280 - P308 + P313 - P405 - P501

危险分类

Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The 60-day temperature-dependent degradation of midazolam and Lorazepam in the prehospital environment.

Jason T McMullan et al.

Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors, 17(1), 1-7 (2012-11-15)

The choice of the optimal benzodiazepine to treat prehospital status epilepticus is unclear. Lorazepam is preferred in the emergency department, but concerns about nonrefrigerated storage limits emergency medical services (EMS) use. Midazolam is increasingly popular, but its heat stability is

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William C Grant

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Olugbenga A Akingbola et al.

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A 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate). Dexmedetomidine was administered because of persistent neuromuscular hyperactivity and severe agitation despite initial therapy with benzodiazepines. Some children show a paradoxical reaction to benzodiazepines, and

Successful treatment of co-occurring catatonia and obsessive-compulsive disorder with concurrent electroconvulsive therapy and benzodiazepine administration.

Michael Makhinson et al.

The journal of ECT, 28(3), e35-e36 (2012-08-24)

Catatonia, associated with a variety of medical and psychiatric conditions such as mood disorders and schizophrenia, is frequently treated with either benzodiazepines or with electroconvulsive therapy (ECT) in treatment-resistant cases. Simultaneous treatment with both is usually avoided. Here, we report

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Lorazepam

European Pharmacopoeia (EP) Reference Standard

About This Item

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制造商/商品名称

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InChI

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一般描述

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包装

其他说明

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WGK

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