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安全信息

D9900

Supelco

地西泮标准液 溶液

1.0 mg/mL in methanol, analytical standard, for drug analysis

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About This Item

经验公式（希尔记法）:
C16H13ClN2O
CAS号:
439-14-5
分子量:
284.74
EC 号:
200-659-6
MDL编号:
MFCD00057323
UNSPSC代码:
41116107
PubChem化学物质编号:
329798914
NACRES:
NA.24

等级

analytical standard, for drug analysis

质量水平

200

drug control

Home Office Schedule 4.1; psychotrope (France); kontrollierte Droge in Deutschland; (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

浓度

1.0 mg/mL in methanol

技术

HPLC: suitable
gas chromatography (GC): suitable

应用

pharmaceutical (small molecule)

包装形式

single component solution

储存温度

2-8°C

SMILES字符串

CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13

InChI

1S/C16H13ClN2O/c1-19-14-8-7-12(17)9-13(14)16(18-10-15(19)20)11-5-3-2-4-6-11/h2-9H,10H2,1H3

InChI key

AAOVKJBEBIDNHE-UHFFFAOYSA-N

基因信息

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)
mouse ... Gabrg2(14406)
rat ... Gabra1(29705) , Gabra2(29706)

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应用

有关合适的仪器技术的更多信息，请参阅产品′检验报告。想要获得更多支持，请联系技术服务部。

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes,Central nervous system

储存分类代码

3 - Flammable liquids

WGK

WGK 2

闪点(°F)

51.8 °F - closed cup

闪点(°C)

11 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
SLCJ4445
SLCD5357
SLBV6203
SLBN3040V
SLBC0394V

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A series of 31 analogues of the neolignan honokiol (a major constituent of Magnolia officinalis) was synthesized, and their effects on GABA(A) receptors expressed in Xenopus oocytes were investigated. Honokiol enhanced chloride currents (I(GABA)) through GABA(A) receptors of seven different
Shoukou Lee et al.
Bioorganic & medicinal chemistry, 16(21), 9519-9523 (2008-10-03)
The pyrimido[1,2-a][1,4]benzodiazepines (1a-c) and the 8-membered analogues (diazocines 2a and 2b) were separated into their atropisomers with HPLC on a chiral column. High stereochemical stability was observed in the atropisomer of the 8-membered derivatives (2a and 2b), and the 1,4-benzodiazepine
Erik Lager et al.
Journal of medicinal chemistry, 49(8), 2526-2533 (2006-04-14)
The 3-ethoxycarbonyl-4-quinolone compound 1 has previously been identified via a database search as an interesting lead compound for ligand binding at the benzodiazepine site of GABA(A) receptors (Kahnberg et al. J. Mol. Graphics Modelling 2004, 23, 253-261). Pharmacophore-guided optimization of
The translocator protein (18 kDa): central nervous system disease and drug design.
Alana M Scarf et al.
Journal of medicinal chemistry, 52(3), 581-592 (2009-01-13)
Jean-Baptiste Faure et al.
Epilepsia, 55(5), 644-653 (2014-03-14)
Temporal lobe epilepsy is a relatively frequent, invalidating, and often refractory neurologic disorder. It is associated with cognitive impairments that affect memory and executive functions. In the rat lithium-pilocarpine temporal lobe epilepsy model, memory impairment and anxiety disorder are classically
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