应用
Aminobenzyl-EDTA has been used to develop an ELISA test for the detection of mercury in water. Aminobenzyl-EDTA has also been used in a study to provide a new class of affinity cleaving reagents that can be directed against protein and nucleic acid targets.
Used to incorporate aminobenzyl-EDTA into peptide by reacting with activated carboxylates such as succinimidylester, p-nitrophenylester, and acid chlorides.
其他说明
Reagent for labeling biomolecules with EDTA
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
A I Song et al.
Bioconjugate chemistry, 8(2), 249-252 (1997-03-01)
A convenient and straightforward synthesis of an amino acid analog, [p-(N-alpha-Fmoc-L-aspartic acid-beta-amido)benzyl]-EDTA tetra-tert-butyl ester, compatible with Fmoc solid phase peptide synthesis strategy is described. This reagent was used to incorporate p-aminobenzyl-EDTA at an internal sequence position in an HIV-1 Tat
M Studer et al.
Bioconjugate chemistry, 3(5), 424-429 (1992-09-01)
Insight into the metabolism of radiolabeled antibodies is important for the design of better radioimaging and therapy agents. To test the effect of linkers that can be cleaved in vivo, we introduced Ala-Leu-Ala-Leu between the antibody Lym-1 and an 111In-labeled
Yi Zhang et al.
Biological trace element research, 144(1-3), 854-864 (2011-03-26)
Immunoassays for heavy metals offer an alternative approach to traditional techniques for detection of mercury. In this study, a mercury-chelate was prepared with 1-(4-aminobenzyl) ethylenediamine-N,N,N',N'-tetraacetic acid (aminobenzyl-EDTA). The resulting complex was linked to keyhole limpet hemocyanin (KLH) or bovine serum
A J Chmura et al.
Proceedings of the National Academy of Sciences of the United States of America, 98(15), 8480-8484 (2001-07-12)
Here we report an approach to the design and production of antibody/ligand pairs, to achieve functional affinity far greater than avidin/biotin. Using fundamental chemical principles, we have developed antibody/ligand pairs that retain the binding specificity of the antibody, but do
M L Thakur et al.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 29(11), 1817-1825 (1988-11-01)
Ten monoclonal antibodies (MAbs) have been evaluated as agents for selective radiolabeling of human neutrophils (PMNs). Four bifunctional chelating agents (BFCA) have been compared in order to determine the one that gives the best labeling of MAbs with radionuclides. Of
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