等级
Molecular Biology
质量水平
检测方案
≥98% dry basis (complexometric)
形式
solid (fine)
反应适用性
reagent type: chelator
制造商/商品名称
Calbiochem®
储存条件
OK to freeze
颜色
white
溶解性
1 M NaOH: soluble
痕量阳离子
heavy metals (as Pb): ≤0.001%
异质活性
DNases, proteases, RNases, none detected
运输
ambient
储存温度
10-30°C
InChI
1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)
InChI key
DEFVIWRASFVYLL-UHFFFAOYSA-N
相关类别
一般描述
对Ca2+有选择性的螯合剂。每个分子结合一个阳离子。诱导嗜铬细胞瘤（PC12）细胞发生凋亡。
应用
- Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor.: This study presents a genetically encoded biosensor for real-time monitoring of lysosomal pH changes, potentially enhanced by buffering agents like EGTA. The findings may offer insights into cellular mechanisms influenced by calcium chelation (Ponsford et al., 2021).
- Comparative Proteomic Analysis of Pleurotus ostreatus Reveals Great Metabolic Differences in the Cap and Stipe Development and the Potential Role of Ca(2+).: The research highlights the role of calcium in fungal development, with EGTA potentially influencing these biological processes through calcium chelation (Zhu et al., 2019).
警告
毒性：标准处理（A）
重悬
在复溶后存放于冰箱（4°C）。储备液可在4°C最长稳定1年。
其他说明
Lindenboim, L., et al. 1995.J. Neurochem.64, 1054.
Bers, D.M.1982.Am. J. Physiol.242, C404.
Bers, D.M.1982.Am. J. Physiol.242, C404.
法律信息
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
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