推荐产品
等级
for molecular biology
质量水平
方案
≥97.0%
表单
powder
反应适用性
reagent type: chelator
缺失
≤1.0% loss on drying
mp
241 °C (dec.) (lit.)
异质活性
DNAse (exonuclease), NICKase (endonuclease), RNAse, and protease, none detected
SMILES字符串
OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O
InChI
1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)
InChI key
DEFVIWRASFVYLL-UHFFFAOYSA-N
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应用
乙二醇双(2-氨基乙醚)四乙酸可用于：
- 杜氏磷酸盐缓冲液(DPBS)，促进细胞间连接削弱
- 作为胞外钙螯合剂研究钙在轴突线粒体变性中的作用
- 作为裂解缓冲液组分，裂解小鼠黏膜细胞用于蛋白质印迹分析。
一种螯合剂，可在镁存在的情况下对钙进行测定。
生化/生理作用
乙二醇双(2-氨基乙醚)四乙酸(EGTA)A是一种螯合剂，可在镁存在的情况下对钙进行测定。
乙二醇四乙酸(EGTA)可1:1螯合钙离子(Ca2+)。作为抗凝剂时，每100 ml血液加1 g。乙二醇四乙酸可抑制钙离子单通道纳米结构域的囊泡释放。这种金属螯合剂可抑制Pseudolysin弹性蛋白酶的活性。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
个人防护装备
Eyeshields, Gloves, type N95 (US)
从最新的版本中选择一种：
分析证书(COA)
Lot/Batch Number
Walter Marcotti et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(16), 5505-5514 (2014-04-18)
Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to
David R Whitfield et al.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 23(2), 141-148 (2014-06-24)
Depression is a common symptom in dementia with Lewy bodies (DLB), Parkinson disease dementia (PDD), and Alzheimer disease (AD), yet its molecular basis remains unclear and current antidepressants do not appear to be effective. Cerebral zinc has been implicated in
Anita C Bellail et al.
Nature communications, 5, 4234-4234 (2014-06-24)
Ubiquitination governs oscillation of cyclin-dependent kinase (CDK) activity through a periodic degradation of cyclins for orderly cell cycle progression; however, the mechanism that maintains the constant CDK protein levels throughout the cell cycle remains unclear. Here we show that CDK6
Jennifer R Brum et al.
Science (New York, N.Y.), 348(6237), 1261498-1261498 (2015-05-23)
Viruses influence ecosystems by modulating microbial population size, diversity, metabolic outputs, and gene flow. Here, we use quantitative double-stranded DNA (dsDNA) viral-fraction metagenomes (viromes) and whole viral community morphological data sets from 43 Tara Oceans expedition samples to assess viral
Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.
Olof Idevall-Hagren et al.
The EMBO journal, 34(17), 2291-2305 (2015-07-24)
The extended synaptotagmins (E-Syts) are ER proteins that act as Ca(2+)-regulated tethers between the ER and the plasma membrane (PM) and have a putative role in lipid transport between the two membranes. Ca(2+) regulation of their tethering function, as well
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