生物来源
synthetic (organic)
质量水平
检测方案
≥97.0%
形式
powder
反应适用性
reagent type: chelator
缺失
≤1.0% loss on drying
mp
241 °C (dec.) (lit.)
溶解性
1 M NaOH: 1.1 g/10 mL, clear, colorless
储存温度
room temp
SMILES字符串
OC(=O)CN(CCOCCOCCN(CC(O)=O)CC(O)=O)CC(O)=O
InChI
1S/C14H24N2O10/c17-11(18)7-15(8-12(19)20)1-3-25-5-6-26-4-2-16(9-13(21)22)10-14(23)24/h1-10H2,(H,17,18)(H,19,20)(H,21,22)(H,23,24)
InChI key
DEFVIWRASFVYLL-UHFFFAOYSA-N
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相关类别
应用
乙二醇双(2-氨基乙醚)四乙酸(EGTA)可用于：
- 作为大鼠主动脉弓缩窄术(TAC)用低温心脏停跳液的组分
- 作为冰冷裂解缓冲液组分，用于蛋白提取和全细胞提取
- 作为HEK293F细胞线粒体提取用缓冲液A、B和C的组分
一种螯合剂，可在镁存在的情况下对钙进行测定。
生化/生理作用
乙二醇双(2-氨基乙醚)四乙酸(EGTA)A是一种螯合剂，可在镁存在的情况下对钙进行测定。
物理属性
在水中的溶解性随 pH 值增加而增加
WGK
WGK 2
个人防护装备
Eyeshields, Gloves, type N95 (US)
Walter Marcotti et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(16), 5505-5514 (2014-04-18)
Tip links between adjacent stereocilia are believed to gate mechano-electrical transducer (MET) channels and mediate the electrical responses of sensory hair cells. We found that mouse auditory hair cells that lack tip links due to genetic mutations or exposure to
David R Whitfield et al.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 23(2), 141-148 (2014-06-24)
Depression is a common symptom in dementia with Lewy bodies (DLB), Parkinson disease dementia (PDD), and Alzheimer disease (AD), yet its molecular basis remains unclear and current antidepressants do not appear to be effective. Cerebral zinc has been implicated in
Triggered Ca2+ influx is required for extended synaptotagmin 1-induced ER-plasma membrane tethering.
Olof Idevall-Hagren et al.
The EMBO journal, 34(17), 2291-2305 (2015-07-24)
The extended synaptotagmins (E-Syts) are ER proteins that act as Ca(2+)-regulated tethers between the ER and the plasma membrane (PM) and have a putative role in lipid transport between the two membranes. Ca(2+) regulation of their tethering function, as well
Jennifer R Brum et al.
Science (New York, N.Y.), 348(6237), 1261498-1261498 (2015-05-23)
Viruses influence ecosystems by modulating microbial population size, diversity, metabolic outputs, and gene flow. Here, we use quantitative double-stranded DNA (dsDNA) viral-fraction metagenomes (viromes) and whole viral community morphological data sets from 43 Tara Oceans expedition samples to assess viral
Anita C Bellail et al.
Nature communications, 5, 4234-4234 (2014-06-24)
Ubiquitination governs oscillation of cyclin-dependent kinase (CDK) activity through a periodic degradation of cyclins for orderly cell cycle progression; however, the mechanism that maintains the constant CDK protein levels throughout the cell cycle remains unclear. Here we show that CDK6
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