推荐产品
生物来源
rabbit
质量水平
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, rat, pig, mouse
制造商/商品名称
Chemicon®
技术
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... ITGB1(3688)
特异性
Reactive with human, mouse, and rat integrin beta-1, as confirmed by western blot. Not reactive with other integrins.
免疫原
Epitope: cytosolic
Synthetic peptide corresponding to the C-terminus of human integrin beta 1 (a.a. CTTVVNPKYEGK)
应用
Detect Integrin β1 using this Anti-Integrin β1 Antibody, cytosolic validated for use in IP & WB.
Western blot: 1-2μg/mL for detection in whole cell lysate. The antibody is effective against reduced (MW = 130kDa) and non-reduced (MW = 110kDa) proteins.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
目标描述
130kDa
外形
Format: Purified
Protein A Purified immunoglobulin. Liquid in PBS containing 0.1% sodium azide.
分析说明
Control
U251 cell line Skin (Basement Membrane)
U251 cell line Skin (Basement Membrane)
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Jean-Baptiste Oudart et al.
Cell adhesion & migration, 15(1), 215-223 (2021-07-27)
We previously demonstrated that F4 peptide (CNPEDCLYPVSHAHQR) from collagen XIX was able to inhibit melanoma cell migrationin vitro and cancer progression in a mouse melanoma model. The aim of the present work was to study the anti-angiogenic properties of F4 peptide. We demonstrated that F4
Xiaoming Bai et al.
Scientific reports, 4, 6538-6538 (2014-10-08)
Prostaglandin E2 (PGE2) has been implicated in cell invasion in hepatocellular carcinoma (HCC), via increased β1-integrin expression and cell migration; however, the mechanism remains unclear. PGE2 exerts its effects via four subtypes of the E prostanoid receptor (EP receptor 1-4).
Jinshun Pan et al.
Scientific reports, 6, 33823-33823 (2016-09-23)
Cyclooxygenase-2 (COX-2) has been implicated in cell invasion in non-small-cell lung cancer (NSCLC). However, the mechanism is unclear. The present study investigated the effect of COX-2 on β1-integrin expression and cell invasion in NSCLC. COX-2 and β1-integrin were co-expressed in
Alexia Vautrin-Glabik et al.
Frontiers in cell and developmental biology, 8, 775-775 (2020-08-28)
Angiogenesis is defined as the formation of new capillaries by sprouting from the pre-existing microvasculature. It occurs in physiological and pathological processes particularly in tumor growth and metastasis. α1, α2, α3, and α6 NC1 domains from type IV collagen were
Siyi Hu et al.
Molecular cancer, 9, 30-30 (2010-02-06)
Factors responsible for invasive and metastatic progression of prostate cancer (PCa) remain largely unknown. Previously, we reported cloning of prosaposin (PSAP) and its genomic amplification and/or overexpression in several androgen-independent metastatic PCa cell lines and lymph node metastases. PSAP is
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