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Merck
CN

5.00112

SAFC

Cocarboxylase chloride

thiamine diphosphoric acid ester chloride EMPROVE® API

Pharma Manufacturing

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别名:
Cocarboxylase chloride, Thiaminium diphosphoric acid ester chloride, Thiaminium pyrophosphate chloride, Thiaminium pyrophosphoric acid ester chloride, TPP
CAS号:
分子量:
460.77
MDL编号:
UNSPSC代码:
12352107
EC索引号:
205-836-1

质量水平

产品线

EMPROVE® API

形式

solid

pH值(酸碱度)

1.0-1.4 (20 °C, 100 g/L in H2O)

mp

240-244 °C (decomposition)

溶解性

220 g/L

堆积密度

500 kg/m3

应用

liquid formulation
pharmaceutical
semi-solid formulation
solid formulation

储存温度

2-25°C

InChI

1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H

InChI key

YXVCLPJQTZXJLH-UHFFFAOYSA-N

相关类别

一般描述

We provide industry-leading production know-how and comprehensive regulatory support for high-quality APIs, backed by nearly 200 years of experience. From a complete portfolio of innovative folates to custom synthesis, our customized and scalable solutions meet your specific production needs. As part of our EMPROVE® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

应用

Cocarboxylase chloride Emprove® API is a source for Vitamin B1 for use in clinical nutrition, vitamin supplements and infusion for Vitamin B1 deficiency. Cocarboxylase Chloride (thiamine diphosphoric acid ester chloride) Emprove® API is manufactured according to ICH Q7 guidelines. An ASMF is available.

法律信息

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形图

Exclamation mark

警示用语:

Warning

危险声明

危险分类

Skin Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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