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Merck
CN

5.00936

维生素 D₃（胆钙化醇）晶体（1 g = 40 Mio.I.U.）

EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

别名:

Vitamin D₃ (cholecalciferol) cryst. (1 g = 40 Mio.I.U.), Colecalciferol, Cholecalciferol

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化学文摘社编号:
67-97-0
分子量:
384.64
UNSPSC Code:
12352401
EC Index Number:
200-673-2
MDL number:
MFCD00078131

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产品名称

维生素 D₃（胆钙化醇）晶体（1 g = 40 Mio.I.U.）, EMPROVE® ESSENTIAL, Ph. Eur., BP, USP

SMILES string

O[C@H]1CCC(=C)\C(=C\C=C2\[C@H]3[C@@]([C@H](CC3)[C@@H](CCCC(C)C)C)(CCC\2)C)\C1

InChI

1S/C27H44O/c1-19(2)8-6-9-21(4)25-15-16-26-22(10-7-17-27(25,26)5)12-13-23-18-24(28)14-11-20(23)3/h12-13,19,21,24-26,28H,3,6-11,14-18H2,1-2,4-5H3/b22-12+,23-13+/t21-,24+,25-,26+,27-/m1/s1

InChI key

QYSXJUFSXHHAJI-FVUVGDFOSA-N

agency

BP
Ph. Eur.
USP

product line

EMPROVE® ESSENTIAL

form

solid

mp

82-87 °C

solubility

<0.1 g/L

application(s)

liquid formulation
pharmaceutical

storage temp.

2-8°C

Quality Level

500

相关类别

Application

Vitamin D3 is used in clinical nutrition for treatment of vitamin D3 deficiency and as skincare agent. Vitamin D3 Emprove® Essential is suitable for pharmaceutical applications.

General description

We offer a range of high quality critical raw materials, solvents and reagents plus the documentation and expertise to meet stringent regulatory requirements. In addition to our comprehensive portfolio, we also offer custom manufacturing services to meet your exact needs. As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

signalword

Danger

Hazard Classifications

Acute Tox. 2 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - STOT RE 1 Oral

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Strategies for the Development of Safe and Effective Pediatric Formulations

Medicine for children poses unique formulation challenges compared to adults. Consider developmental physiology and age specifics when designing pharmaceuticals. Quality issues can severely impact patient safety. Therefore, excipient quality, supplier selection, and supply chain security are crucial, particularly for pediatric formulations.

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Pediatric Formulations

Developing formulations specifically for infants and children is increasingly important. To help you master these challenges effectively, we offer an extensive portfolio of well-established high-quality excipients and APIs for pediatric pharmaceutical formulations that are proven in practice.

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