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Merck
CN
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文件

安全信息

M-015

Supelco

安眠酮标准液 溶液

1 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

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经验公式（希尔记法）:
C16H14N2O
CAS号:
72-44-6
分子量:
250.30
MDL编号:
MFCD00057320
UNSPSC代码:
41116107
PubChem化学物质编号:
329817730
NACRES:
NA.24

等级

certified reference material

质量水平

300

形式

liquid

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIC (Portugal)

浓度

1 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

格式

single component solution

储存温度

2-8°C

SMILES字符串

Cc1ccccc1N2C(C)=Nc3ccccc3C2=O

InChI

1S/C16H14N2O/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19/h3-10H,1-2H3

InChI key

JEYCTXHKTXCGPB-UHFFFAOYSA-N

基因信息

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

相关类别

一般描述

甲喹酮是一种镇静催眠药和中枢神经系统抑制剂，其以商品名Quaalude进行销售，可用于治疗失眠症。甲喹酮也有滥用的历史，其以迪斯科饼干、Lemmons和714s等街头名称闻名。此认证的溶液标准品可作为校准物或对照品中的起始材料，通过LC/MS或GC/MS，用于从尿液药物测试到法医分析和临床毒理学方面的各种应用中。

应用


  • Pharmacokinetic studies: The analysis of Methaqualone in pharmacokinetic research employs liquid chromatography/tandem mass spectrometry, crucial for understanding its metabolism and excretion patterns. Such studies are vital for developing safety profiles and therapeutic guidelines for sedative-hypnotics (Yun et al., 2007).

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

靶器官

Eyes

WGK

WGK 1

闪点(°F)

49.5 °F

闪点(°C)

9.7 °C

法规信息

监管及禁止进口产品

分析证书(COA)

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Phenytoin intoxication induced by Mandrax (methaqualone).
Rajesh Verma et al.
Epilepsy research, 98(2-3), 281-282 (2011-10-25)
Antimalarials: shortages and searches.
Stanley Scheindlin
Molecular interventions, 5(5), 268-272 (2005-10-27)
Mark R Darling et al.
SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging, 57(4), 132-135 (2002-06-25)
The effects of cannabis/methaqualone/tobacco smoking on the epithelial cells of the tongue, buccal mucosa and floor of the mouth were examined. Oral mucosal smears for detection of cellular changes were taken from 4 sites in 16 patients. The tongue blade
Guo-Zhou Zhi et al.
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 22(4), 335-337 (2002-10-23)
KR-100 is a newly developed long-lasting insecticide that incorporates cinerins substance, drug-release control substance and synergistic agent following certain procedures under carefully regulated conditions. Tests of the efficacy, toxicity, stability and long-term effect of KR-100 were conducted, and it was
N Fucci
The American journal of forensic medicine and pathology, 17(3), 231-232 (1996-09-01)
A case of acute intoxication of both methaqualone and diphenhydramine is reported. The analysis of these compounds was performed by liquid-liquid extraction (Toxi-Lab DPC procedure) followed by gas chromatography/mass spectrometry determination; both substances are contained in the pharmaceutical formulation called
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