跳转至内容
Merck
CN
所有图片(1)

主要文件

查看所有文档

安全信息

E-901

Supelco

艾司唑仑标准液 溶液

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C16H11ClN4
CAS号:
29975-16-4
分子量:
294.74
EC 号:
200-659-6
MDL编号:
MFCD00867537
UNSPSC代码:
41116107
NACRES:
NA.24

等级

certified reference material

质量水平

300

表单

liquid

特点

Snap-N-Spike®/Snap-N-Shoot®

包装

ampule of 1 mL

制造商/商品名称

Cerilliant®

drug control

Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)

浓度

1.0 mg/mL in methanol

技术

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

应用

clinical testing

包装形式

single component solution

储存温度

−20°C

SMILES字符串

Clc1ccc-2c(c1)C(=NCc3nncn-23)c4ccccc4

InChI

1S/C16H11ClN4/c17-12-6-7-14-13(8-12)16(11-4-2-1-3-5-11)18-9-15-20-19-10-21(14)15/h1-8,10H,9H2

InChI key

CDCHDCWJMGXXRH-UHFFFAOYSA-N

基因信息

human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879)

一般描述

CRM质量级别的Snap-N-Spike®溶液适合用作从法医分析和临床毒理学研究到尿液药物检测的各种LC/MS或GC/MS应用的校准品或对照品的起始材料。艾司唑仑是一种苯二氮卓类药物，可用于失眠症的短期治疗。艾司唑仑以ProSom或悠乐丁等商品名出售，经常被娱乐性滥用以达到高剂量或违反医生的建议而长期使用。

应用


  • 环境痕量分析中的艾司唑仑：一项采用超高效液相色谱-串联质谱（UPLC-MS/MS）进行的研究详细介绍了环境样本中艾司唑仑和其它精神药物的检测，强调了该方法在监测药物残留环境污染方面的准确性和应用（Wang et al., 2024）。

  • 艾司唑仑与冠状病毒病后的失眠证：研究分析了新冠肺炎幸存者的失眠患病率，确定艾司唑仑是治疗方案的重要一环。这项研究表明，从重大疾病长期恢复相关睡眠障碍的解决上看，艾司唑仑一直有关联（Lu et al., 2024）。

  • 艾司唑仑治疗脑卒中后失眠的比较分析：一项网络荟萃分析比较了中风后失眠的各种疗法（包括艾司唑仑），提供了有关其相比于其它治疗方案的有效性的见解。本研究有助于我们了解中风后患者失眠的最佳治疗策略 （Chang et al., 2023）。

法律信息

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

储存分类代码

3 - Flammable liquids

WGK

WGK 1

闪点(°F)

49.5 °F - closed cup

闪点(°C)

9.7 °C - closed cup

法规信息

监管及禁止进口产品

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

It looks like we've run into a problem, but you can still download Certificates of Analysis from our 文件 section.

如需帮助，请联系 客户支持

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Masatomo Miura et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 18(5), 525-528 (2002-05-31)
A high-performance liquid chromatography (HPLC) assay was developed for the determination of estazolam in human plasma. Estazolam and alprazolam as an internal standard were detected by ultraviolet absorbance at 240 nm. Estazolam in plasma was extracted by a rapid and
H Inoue et al.
Forensic science international, 113(1-3), 367-373 (2000-09-09)
Benzodiazepines are one of the most widely prescribed drugs for the treatment of a wide spectrum of clinical disorders. They are used as anticonvulsants, anxiolytics, hypnotics or muscle relaxants with different duration of action. In this paper, a simple and
Clinical efficacies of treating refractory insomnia patients with estazolam plus alternating current magnetic field.
Zhi-Zhong Wang et al.
Chinese medical journal, 125(17), 3175-3176 (2012-08-31)
Toshiaki Aoshima et al.
Progress in neuro-psychopharmacology & biological psychiatry, 27(3), 535-538 (2003-04-15)
The effects of the cytochrome P450 (CYP)2C19 genotype and cigarette smoking on the single oral dose pharmacokinetics and pharmacodynamics of estazolam were studied in 16 healthy male volunteers. The two mutated alleles (CYP2C19*2 and CYP2C19*3) causing absent CYP2C19 activity were
Yuan Tian et al.
Journal of pharmaceutical and biomedical analysis, 47(4-5), 899-906 (2008-05-13)
A simple, rapid, sensitive and selective liquid chromatographic-tandem mass spectrometric (LC-MS/MS) method was developed and validated for the quantification of rupatadine in human plasma using estazolam as internal standard (IS). Following liquid-liquid extraction, the analytes were separated using a mobile
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门